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Vwa7 von Willebrand factor A domain containing 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 309611, updated on 5-Mar-2024

Summary

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Official Symbol
Vwa7provided by RGD
Official Full Name
von Willebrand factor A domain containing 7provided by RGD
Primary source
RGD:1303137
See related
Ensembl:ENSRNOG00000000860 AllianceGenome:RGD:1303137
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
G7c; NG37; C6orf27
Summary
Predicted to be located in extracellular region. Orthologous to human VWA7 (von Willebrand factor A domain containing 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 102.0), Muscle (RPKM 41.8) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Vwa7 in Genome Data Viewer
Location:
20p12
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (3799646..3810289, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (3794991..3805646, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (5008508..5019040)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene chloride intracellular channel 1 Neighboring gene U6 spliceosomal RNA Neighboring gene mutS homolog 5 Neighboring gene suppressor APC domain containing 1 Neighboring gene valyl-tRNA synthetase 1 Neighboring gene uncharacterized LOC108349032

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. G7c, a novel gene in the mouse and human major histocompatibility complex class III region, possibly controlling lung tumor susceptibility. Snoek M, et al. Immunogenetics, 2000 Apr. PMID 10803853
  2. Molecular analysis of the major MHC recombinational hot spot located within the G7c gene of the murine class III region that is involved in disease susceptibility. Snoek M, et al. J Immunol, 1998 Jan 1. PMID 9551980
  3. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, et al. Genome Res, 2004 Apr. PMID 15060004, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
von Willebrand factor A domain-containing protein 7
Names
protein G7c

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212499.2 → NP_997664.1  von Willebrand factor A domain-containing protein 7 precursor

    See identical proteins and their annotated locations for NP_997664.1

    Status: VALIDATED

    Source sequence(s)
    BX883045
    UniProtKB/Swiss-Prot
    Q6MG64
    UniProtKB/TrEMBL
    A6KTQ7
    Related
    ENSRNOP00000001153.2, ENSRNOT00000001153.5
    Conserved Domains (2) summary
    pfam07217
    Location:163 → 190
    Het-C; Heterokaryon incompatibility protein Het-C
    cl00057
    Location:318 → 496
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    3799646..3810289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039098675.2 → XP_038954603.1  von Willebrand factor A domain-containing protein 7 isoform X1

    UniProtKB/TrEMBL
    A6KTQ7
    Conserved Domains (2) summary
    pfam07217
    Location:163 → 190
    Het-C; Heterokaryon incompatibility protein Het-C
    cl00057
    Location:316 → 422
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  2. XM_039098674.2 → XP_038954602.1  von Willebrand factor A domain-containing protein 7 isoform X1

    UniProtKB/TrEMBL
    A6KTQ7
    Conserved Domains (2) summary
    pfam07217
    Location:163 → 190
    Het-C; Heterokaryon incompatibility protein Het-C
    cl00057
    Location:316 → 422
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  3. XM_063279117.1 → XP_063135187.1  von Willebrand factor A domain-containing protein 7 isoform X1

  4. XM_063279118.1 → XP_063135188.1  von Willebrand factor A domain-containing protein 7 isoform X2

RNA

  1. XR_010060676.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6MG64.1 GenPept UniProtKB/Swiss-Prot:Q6MG64

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