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Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 310358, updated on 5-Mar-2024

Summary

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Official Symbol
Plcxd3provided by RGD
Official Full Name
phosphatidylinositol-specific phospholipase C, X domain containing 3provided by RGD
Primary source
RGD:1308448
See related
Ensembl:ENSRNOG00000014550 AllianceGenome:RGD:1308448
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308448
Summary
Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Predicted to be active in glutamatergic synapse. Orthologous to human PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 166.4), Adrenal (RPKM 27.2) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Plcxd3 in Genome Data Viewer
Location:
2q16
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (55294597..55473968)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (53567022..53746384)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (54191538..54360780)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene 3-oxoacid CoA transferase 1 Neighboring gene eukaryotic translation elongation factor 1 alpha 1, pseudogene 13 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene complement C6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. Biesemann C, et al. EMBO J, 2014 Jan 13. PMID 24413018, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables phosphoric diester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
  
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
PI-PLC X domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107671.1 → NP_001101141.1  PI-PLC X domain-containing protein 3

    See identical proteins and their annotated locations for NP_001101141.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474048
    UniProtKB/TrEMBL
    A6KGC8, D4A1H2
    Related
    ENSRNOP00000019524.5, ENSRNOT00000019524.6
    Conserved Domains (1) summary
    cd08616
    Location:19 → 311
    PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    55294597..55473968
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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