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Cog6 component of oligomeric golgi complex 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 310411, updated on 5-Mar-2024

Summary

Official Symbol
Cog6provided by RGD
Official Full Name
component of oligomeric golgi complex 6provided by RGD
Primary source
RGD:1303283
See related
Ensembl:ENSRNOG00000013660 AllianceGenome:RGD:1303283
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in glycosylation and intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIl. Orthologous to human COG6 (component of oligomeric golgi complex 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 313.7), Heart (RPKM 123.4) and 9 other tissues See more
Orthologs
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Genomic context

Location:
2q26
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (139212459..139249505, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (137062127..137099176, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (142197566..142235054, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547111 Neighboring gene uncharacterized LOC134485913 Neighboring gene uncharacterized LOC120100818 Neighboring gene LHFPL tetraspan subfamily member 6 Neighboring gene uncharacterized LOC120100819 Neighboring gene uncharacterized LOC134485911

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC94990

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Golgi organization IEA
Inferred from Electronic Annotation
more info
 
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
 
involved_in glycosylation IEA
Inferred from Electronic Annotation
more info
 
involved_in glycosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in glycosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intra-Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde transport, vesicle recycling within Golgi IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde transport, vesicle recycling within Golgi ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
part_of Golgi transport complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Golgi transport complex IEA
Inferred from Electronic Annotation
more info
 
part_of Golgi transport complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
conserved oligomeric Golgi complex subunit 6
Names
COG complex subunit 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004262.1NP_001004262.1  conserved oligomeric Golgi complex subunit 6

    See identical proteins and their annotated locations for NP_001004262.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079442
    UniProtKB/Swiss-Prot
    Q68FP9
    UniProtKB/TrEMBL
    A0A8I6G9T5
    Related
    ENSRNOP00000079046.1, ENSRNOT00000098369.1
    Conserved Domains (1) summary
    smart01087
    Location:68656
    COG6; Conserved oligomeric complex COG6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    139212459..139249505 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)