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Fam110a family with sequence similarity 110, member A [ Rattus norvegicus (Norway rat) ]

Gene ID: 311535, updated on 5-Mar-2024

Summary

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Official Symbol
Fam110aprovided by RGD
Official Full Name
family with sequence similarity 110, member Aprovided by RGD
Primary source
RGD:1308904
See related
Ensembl:ENSRNOG00000050946 AllianceGenome:RGD:1308904
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308904
Summary
Orthologous to human FAM110A (family with sequence similarity 110 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 54.2), Thymus (RPKM 25.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam110a in Genome Data Viewer
Location:
3q41
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (160934815..160945405, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (140474484..140485074, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (147476580..147487170, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101753 Neighboring gene angiopoietin 4 Neighboring gene uncharacterized LOC120101754 Neighboring gene ribosomal protein S29, pseudogene 15 Neighboring gene solute carrier family 52 member 3 Neighboring gene uncharacterized LOC120101756

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in mitotic spindle organization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in spindle microtubule ISO
Inferred from Sequence Orthology
more info
  
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein FAM110A
Names
serine threonine rich protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014050.2 → NP_001014072.2  protein FAM110A isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' exon and has an upstream AUG start codon, compared to variant 1. The resulting isoform (2) is longer at the N-terminus, compared to isoform 1.
    Source sequence(s)
    BC079251, CB556608, CB766675
    UniProtKB/TrEMBL
    M0RB04, Q6AXZ9
    Related
    ENSRNOP00000066725.2, ENSRNOT00000074295.3
    Conserved Domains (2) summary
    pfam14160
    Location:213 → 318
    FAM110_C; Centrosome-associated C terminus
    pfam14161
    Location:34 → 134
    FAM110_N; Centrosome-associated N terminus

  2. NM_001244768.1 → NP_001231697.1  protein FAM110A isoform 1

    See identical proteins and their annotated locations for NP_001231697.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) and variants 2 and 3 encode the same protein (isoform 1).
    Source sequence(s)
    CB556608, CB766675, CB806736, CV110036
    UniProtKB/TrEMBL
    A0A0G2JY94, G4XVC3, Q6AXZ9
    Related
    ENSRNOP00000072792.1, ENSRNOT00000077580.2
    Conserved Domains (2) summary
    pfam14160
    Location:183 → 288
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:4 → 104
    FAM110_N; Centrosome-associated N-terminus

  3. NM_001244769.1 → NP_001231698.1  protein FAM110A isoform 1

    See identical proteins and their annotated locations for NP_001231698.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein (isoform 1).
    Source sequence(s)
    CB556608, CB766675, CB806736, CV113127
    UniProtKB/TrEMBL
    A0A0G2JY94, G4XVC3, Q6AXZ9
    Related
    ENSRNOP00000070568.1, ENSRNOT00000084722.2
    Conserved Domains (2) summary
    pfam14160
    Location:183 → 288
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:4 → 104
    FAM110_N; Centrosome-associated N-terminus

  4. NM_001244770.1 → NP_001231699.1  protein FAM110A isoform 1

    See identical proteins and their annotated locations for NP_001231699.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein (isoform 1).
    Source sequence(s)
    BU670818, CB556608, CB766675, DY318143
    UniProtKB/TrEMBL
    A0A0G2JY94, G4XVC3, Q6AXZ9
    Related
    ENSRNOP00000087216.1, ENSRNOT00000093860.1
    Conserved Domains (2) summary
    pfam14160
    Location:183 → 288
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:4 → 104
    FAM110_N; Centrosome-associated N-terminus

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    160934815..160945405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006235231.5 → XP_006235293.1  protein FAM110A isoform X1

    UniProtKB/TrEMBL
    A0A8I6A2V0
    Related
    ENSRNOP00000085228.1
    Conserved Domains (2) summary
    pfam14160
    Location:345 → 450
    FAM110_C; Centrosome-associated C terminus
    pfam14161
    Location:166 → 266
    FAM110_N; Centrosome-associated N terminus

  2. XM_017591774.3 → XP_017447263.1  protein FAM110A isoform X2

    UniProtKB/TrEMBL
    A0A0G2JY94, G4XVC3, Q6AXZ9
    Related
    ENSRNOP00000083568.1
    Conserved Domains (2) summary
    pfam14160
    Location:183 → 288
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:4 → 104
    FAM110_N; Centrosome-associated N-terminus

  3. XM_039105051.2 → XP_038960979.1  protein FAM110A isoform X2

    UniProtKB/TrEMBL
    A0A0G2JY94, G4XVC3, Q6AXZ9
    Related
    ENSRNOP00000083945.1
    Conserved Domains (2) summary
    pfam14160
    Location:183 → 288
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:4 → 104
    FAM110_N; Centrosome-associated N-terminus

  4. XM_006235234.5 → XP_006235296.1  protein FAM110A isoform X2

    See identical proteins and their annotated locations for XP_006235296.1

    UniProtKB/TrEMBL
    A0A0G2JY94, G4XVC3, Q6AXZ9
    Conserved Domains (2) summary
    pfam14160
    Location:183 → 288
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:4 → 104
    FAM110_N; Centrosome-associated N-terminus
Nucleotide Protein Strain
Heading Accession and Version

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