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Cdca7 cell division cycle associated 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311742, updated on 5-Mar-2024

Summary

Official Symbol
Cdca7provided by RGD
Official Full Name
cell division cycle associated 7provided by RGD
Primary source
RGD:1309363
See related
Ensembl:ENSRNOG00000001514 AllianceGenome:RGD:1309363
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in apoptotic process and regulation of transcription, DNA-templated. Predicted to act upstream of or within regulation of cell population proliferation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 3. Orthologous to human CDCA7 (cell division cycle associated 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 305.9), Spleen (RPKM 80.1) and 3 other tissues See more
Orthologs
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Genomic context

See Cdca7 in Genome Data Viewer
Location:
3q23
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (77730315..77740950)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (57322718..57333353)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (59153281..59163916)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101564 Neighboring gene mitogen-activated protein kinase kinase kinase 20 Neighboring gene uncharacterized LOC134486106 Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene ribosomal protein S13, pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC112656

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cell division cycle-associated protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025693.1NP_001020864.1  cell division cycle-associated protein 7

    See identical proteins and their annotated locations for NP_001020864.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098690
    UniProtKB/Swiss-Prot
    Q4KM91
    UniProtKB/TrEMBL
    A0A8L2UHI2, A6HM74
    Related
    ENSRNOP00000002066.6, ENSRNOT00000002066.7
    Conserved Domains (1) summary
    pfam10497
    Location:268366
    zf-4CXXC_R1; Zinc-finger domain of monoamine-oxidase A repressor R1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    77730315..77740950
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063283912.1XP_063139982.1  cell division cycle-associated protein 7 isoform X1