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Fibcd1 fibrinogen C domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311861, updated on 30-Mar-2024

Summary

Symbol
Fibcd1provided by RGD
Full Name
fibrinogen C domain containing 1provided by RGD
Primary source
RGD:1309097
See related
Ensembl:ENSRNOG00000009735 AllianceGenome:RGD:1309097
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fibcd1l1; RGD1309097
Summary
Predicted to enable chitin binding activity and signaling receptor binding activity. Predicted to be involved in cell adhesion. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human FIBCD1 (fibrinogen C domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 27.2) See more
Orthologs
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Genomic context

Location:
3p12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (35490459..35524142, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (15092682..15126371, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (9365866..9399578)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene ABL proto-oncogene 1, non-receptor tyrosine kinase Neighboring gene uncharacterized LOC134486069 Neighboring gene pyroglutamylated RFamide peptide Neighboring gene uncharacterized LOC120101519 Neighboring gene uncharacterized LOC134486281

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables chitin binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in collagen-containing extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
fibrinogen C domain-containing protein 1
Names
fibrinogen C domain containing 1-like 1
fibrinogen C domain-containing protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107829.2NP_001101299.1  fibrinogen C domain-containing protein 1

    See identical proteins and their annotated locations for NP_001101299.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6JU32, D4ADA1
    Related
    ENSRNOP00000012928.5, ENSRNOT00000012927.7
    Conserved Domains (1) summary
    cd00087
    Location:239455
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    35490459..35524142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)