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Fam3c FAM3 metabolism regulating signaling molecule C [ Rattus norvegicus (Norway rat) ]

Gene ID: 312159, updated on 2-May-2024

Summary

Official Symbol
Fam3cprovided by RGD
Official Full Name
FAM3 metabolism regulating signaling molecule Cprovided by RGD
Primary source
RGD:735193
See related
Ensembl:ENSRNOG00000060349 AllianceGenome:RGD:735193
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in negative regulation of gluconeogenesis. Predicted to be located in Golgi apparatus. Predicted to be active in extracellular space. Orthologous to human FAM3C (FAM3 metabolism regulating signaling molecule C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 267.4), Brain (RPKM 218.7) and 9 other tissues See more
Orthologs
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Genomic context

See Fam3c in Genome Data Viewer
Location:
4q22
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (51805686..51853030, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (50839929..50887276, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (49388962..49439892, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene cadherin-like and PC-esterase domain containing 1 Neighboring gene Wnt family member 16 Neighboring gene ribosomal protein S2, pseudogene 30 Neighboring gene translationally-controlled tumor protein-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein FAM3C
Names
FAM3C-like protein
family with sequence similarity 3, member C
interleukin-like EMT inducer

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198771.2NP_942066.1  protein FAM3C precursor

    See identical proteins and their annotated locations for NP_942066.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/Swiss-Prot
    Q810F4
    UniProtKB/TrEMBL
    A0A0G2JUB0, A6IE64, A6IE65
    Related
    ENSRNOP00000069031.2, ENSRNOT00000077889.2
    Conserved Domains (1) summary
    cd13940
    Location:53223
    ILEI_FAM3C; Interleukin-like EMT inducer

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    51805686..51853030 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)