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Galnt14 polypeptide N-acetylgalactosaminyltransferase 14 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313878, updated on 3-Apr-2024

Summary

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Official Symbol
Galnt14provided by RGD
Official Full Name
polypeptide N-acetylgalactosaminyltransferase 14provided by RGD
Primary source
RGD:1310068
See related
Ensembl:ENSRNOG00000007951 AllianceGenome:RGD:1310068
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable carbohydrate binding activity; metal ion binding activity; and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Orthologous to human GALNT14 (polypeptide N-acetylgalactosaminyltransferase 14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 83.2), Brain (RPKM 26.8) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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Location:
6q14
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (27507878..27724033)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (21756039..21977533)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (24770308..24985711, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103483 Neighboring gene EH-domain containing 3 Neighboring gene uncharacterized LOC134479329 Neighboring gene calpain 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables polypeptide N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
polypeptide N-acetylgalactosaminyltransferase 14
Names
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
NP_001012109.1
XP_038968091.1
XP_038968092.1
XP_063117931.1
XP_063117932.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012109.1 → NP_001012109.1  polypeptide N-acetylgalactosaminyltransferase 14

    See identical proteins and their annotated locations for NP_001012109.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079128
    UniProtKB/TrEMBL
    A0A8I5ZTB2, A6H9Z9, F7F293, Q6AYA4
    Related
    ENSRNOP00000010613.5, ENSRNOT00000010613.7
    Conserved Domains (4) summary
    cd02510
    Location:114 → 408
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:422 → 549
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:422 → 547
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    pfam13641
    Location:111 → 337
    Glyco_tranf_2_3; Glycosyltransferase like family 2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    27507878..27724033
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063261862.1 → XP_063117932.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZTM0

  2. XM_063261861.1 → XP_063117931.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X1

  3. XM_039112163.2 → XP_038968091.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZTB2
    Conserved Domains (2) summary
    cd02510
    Location:86 → 380
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    pfam00652
    Location:394 → 519
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

  4. XM_039112164.2 → XP_038968092.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X3

    Conserved Domains (2) summary
    cd02510
    Location:2 → 269
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    pfam00652
    Location:283 → 408
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
Nucleotide Protein Strain
Heading Accession and Version

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