U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abhd1 abhydrolase domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313917, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Abhd1provided by RGD
Official Full Name
abhydrolase domain containing 1provided by RGD
Primary source
RGD:1310988
See related
Ensembl:ENSRNOG00000025689 AllianceGenome:RGD:1310988
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable acetylesterase activity and acylglycerol lipase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process and medium-chain fatty acid catabolic process. Predicted to be integral component of membrane. Orthologous to human ABHD1 (abhydrolase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 168.4), Liver (RPKM 149.8) and 9 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
6q14
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (31142476..31147464, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (25422526..25427514, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (26787807..26792795, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene transcription factor 23 Neighboring gene proline rich 30 Neighboring gene prolactin regulatory element binding Neighboring gene cell growth regulator with EF hand domain 1 Neighboring gene ketohexokinase

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC105659

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables acetylesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables acylglycerol lipase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in medium-chain fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in medium-chain fatty acid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein ABHD1
Names
abhydrolase domain-containing protein 1
alpha/beta hydrolase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008520.1 → NP_001008520.1  protein ABHD1

    See identical proteins and their annotated locations for NP_001008520.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086351
    UniProtKB/Swiss-Prot
    Q5RK23
    UniProtKB/TrEMBL
    A6HAA3
    Related
    ENSRNOP00000009339.2, ENSRNOT00000010403.5
    Conserved Domains (1) summary
    cl21494
    Location:54 → 381
    Abhydrolase; alpha/beta hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    31142476..31147464 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039112176.2 → XP_038968104.1  protein ABHD1 isoform X1

    UniProtKB/TrEMBL
    A6HAA4
    Conserved Domains (1) summary
    cl21494
    Location:26 → 190
    Abhydrolase; alpha/beta hydrolases

  2. XM_063261874.1 → XP_063117944.1  protein ABHD1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RK23.1 GenPept UniProtKB/Swiss-Prot:Q5RK23

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous