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Tmem30b transmembrane protein 30B [ Rattus norvegicus (Norway rat) ]

Gene ID: 314224, updated on 31-Mar-2024

Summary

Official Symbol
Tmem30bprovided by RGD
Official Full Name
transmembrane protein 30Bprovided by RGD
Primary source
RGD:1308732
See related
Ensembl:ENSRNOG00000008046 AllianceGenome:RGD:1308732
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable aminophospholipid flippase activity. Predicted to be involved in aminophospholipid transport; phospholipid translocation; and positive regulation of protein exit from endoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Orthologous to human TMEM30B (transmembrane protein 30B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Tmem30b in Genome Data Viewer
Location:
6q24
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (97987471..97990546, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (92251626..92254702, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (96439607..96442682, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103552 Neighboring gene uncharacterized LOC102550345 Neighboring gene protein kinase C, eta Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene uncharacterized LOC120103553 Neighboring gene hypoxia inducible factor 1 subunit alpha

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables aminophospholipid flippase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in aminophospholipid translocation IEA
Inferred from Electronic Annotation
more info
 
involved_in aminophospholipid transport ISO
Inferred from Sequence Orthology
more info
 
involved_in phospholipid translocation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of protein exit from endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of phospholipid-translocating ATPase complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cell cycle control protein 50B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080380.3NP_001073849.1  cell cycle control protein 50B

    See identical proteins and their annotated locations for NP_001073849.1

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A6HC62, D3Z9E9
    Related
    ENSRNOP00000010923.1, ENSRNOT00000010923.4
    Conserved Domains (1) summary
    pfam03381
    Location:60342
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    97987471..97990546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)