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Krr1 KRR1, small subunit processome component homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 314830, updated on 4-Jan-2025

Summary

Official Symbol
Krr1provided by RGD
Official Full Name
KRR1, small subunit processome component homologprovided by RGD
Primary source
RGD:1306183
See related
EnsemblRapid:ENSRNOG00000004035 AllianceGenome:RGD:1306183
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hrb2
Summary
Predicted to enable RNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in chromosome; intercellular bridge; and nuclear lumen. Predicted to be part of small-subunit processome. Orthologous to human KRR1 (KRR1 small subunit processome component homolog). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 146.2), Spleen (RPKM 121.9) and 9 other tissues See more
Orthologs
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Genomic context

See Krr1 in Genome Data Viewer
Location:
7q22
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (49361794..49374222)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (47475557..47486996)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (54756043..54767477)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351449 Neighboring gene uncharacterized LOC120093587 Neighboring gene uncharacterized LOC108351450 Neighboring gene GLI pathogenesis-related 1 Neighboring gene GLIPR1 like 2 Neighboring gene GLIPR1 like 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding  
Component Evidence Code Pubs
located_in chromosome  
located_in chromosome  
located_in intercellular bridge  
located_in intercellular bridge  
located_in nucleolus  
located_in nucleoplasm  
located_in nucleoplasm  
part_of small-subunit processome  

General protein information

Preferred Names
KRR1 small subunit processome component homolog
Names
HIV-1 Rev binding protein 2
KRR1, small subunit (SSU) processome component, homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108094.2NP_001101564.1  KRR1 small subunit processome component homolog

    See identical proteins and their annotated locations for NP_001101564.1

    Status: PROVISIONAL

    Source sequence(s)
    BC128768
    UniProtKB/TrEMBL
    A0A8I6ALQ2, A1A5R3, A6IGI0, F7FJ71
    Related
    ENSRNOP00000059249.1, ENSRNOT00000063917.3
    Conserved Domains (2) summary
    COG1094
    Location:55240
    Krr1; rRNA processing protein Krr1/Pno1, contains KH domain [Translation, ribosomal structure and biogenesis]
    cd22394
    Location:139230
    KH-I_KRR1_rpt2; second type I K homology (KH) RNA-binding domain found in KRR1 small subunit processome component and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    49361794..49374222
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079121.2XP_038935049.1  KRR1 small subunit processome component homolog isoform X1

    Conserved Domains (2) summary
    cd22394
    Location:42133
    KH-I_KRR1_rpt2; second type I K homology (KH) RNA-binding domain found in KRR1 small subunit processome component and similar proteins
    cl00098
    Location:138
    KH-I; K homology (KH) RNA-binding domain, type I
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