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Krt80 keratin 80 [ Rattus norvegicus (Norway rat) ]

Gene ID: 315318, updated on 13-Apr-2024

Summary

Official Symbol
Krt80provided by RGD
Official Full Name
keratin 80provided by RGD
Primary source
RGD:1359177
See related
Ensembl:ENSRNOG00000025994 AllianceGenome:RGD:1359177
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Kb2; Kb20
Summary
Predicted to be located in cytoplasm and intermediate filament. Orthologous to human KRT80 (keratin 80). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 43.3), Kidney (RPKM 43.0) and 3 other tissues See more
Orthologs
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Genomic context

See Krt80 in Genome Data Viewer
Location:
7q36
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (134341951..134363872, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (132463216..132485134, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (142995715..143015932, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene autophagy related 101 Neighboring gene small integral membrane protein 41 Neighboring gene uncharacterized LOC120093741 Neighboring gene 40S ribosomal protein S25-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of skin epidermis IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in keratinization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
NOT located_in desmosome ISO
Inferred from Sequence Orthology
more info
 
located_in intermediate filament ISO
Inferred from Sequence Orthology
more info
 
located_in intermediate filament cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
is_active_in keratin filament IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in keratin filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin, type II cytoskeletal 80
Names
CK-80
K80
cytokeratin-80
keratin 80, type II
type II keratin-20
type-II keratin Kb20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008815.2NP_001008815.1  keratin, type II cytoskeletal 80

    See identical proteins and their annotated locations for NP_001008815.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/Swiss-Prot
    Q6IMF1
    UniProtKB/TrEMBL
    A0A8L2QJM1
    Related
    ENSRNOP00000038848.3, ENSRNOT00000029697.4
    Conserved Domains (2) summary
    pfam00038
    Location:82393
    Filament; Intermediate filament protein
    pfam16208
    Location:978
    Keratin_2_head; Keratin type II head

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    134341951..134363872 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263678.1XP_063119748.1  keratin, type II cytoskeletal 80 isoform X1