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Igsf9b immunoglobulin superfamily, member 9B [ Rattus norvegicus (Norway rat) ]

Gene ID: 315510, updated on 11-Apr-2024

Summary

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Official Symbol
Igsf9bprovided by RGD
Official Full Name
immunoglobulin superfamily, member 9Bprovided by RGD
Primary source
RGD:1564717
See related
Ensembl:ENSRNOG00000009253 AllianceGenome:RGD:1564717
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564717
Summary
Predicted to enable kinase binding activity. Predicted to be involved in synaptic membrane adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules and positive regulation of inhibitory postsynaptic potential. Is active in GABA-ergic synapse and postsynaptic specialization of symmetric synapse. Orthologous to human IGSF9B (immunoglobulin superfamily member 9B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 58.7), Kidney (RPKM 41.8) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
8q13
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (33971779..34027390)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (25712644..25769481)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (28352497..28398659)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480004 Neighboring gene small nucleolar RNA SNORD113/SNORD114 family Neighboring gene uncharacterized LOC120094099 Neighboring gene spermatogenesis associated 19 Neighboring gene uncharacterized LOC134480005

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development. Woo J, et al. J Cell Biol, 2013 Jun 10. PMID 23751499, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables kinase binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules ISO
Inferred from Sequence Orthology
more info
  
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of inhibitory postsynaptic potential ISO
Inferred from Sequence Orthology
more info
  
involved_in synaptic membrane adhesion ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in GABA-ergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in GABA-ergic synapse ISO
Inferred from Sequence Orthology
more info
  
located_in dendrite ISO
Inferred from Sequence Orthology
more info
  
located_in inhibitory synapse ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
  
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
  
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in postsynaptic specialization of symmetric synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein turtle homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001376950.1 → NP_001363879.1  protein turtle homolog B precursor

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    D3ZB51
    UniProtKB/TrEMBL
    A0A8L2Q5X0
    Related
    ENSRNOP00000012391.6, ENSRNOT00000012391.7
    Conserved Domains (5) summary
    PHA03247
    Location:898 → 1246
    PHA03247; large tegument protein UL36; Provisional
    cd00063
    Location:510 → 605
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:438 → 502
    Ig; Immunoglobulin domain
    pfam07679
    Location:139 → 225
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:229 → 321
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    33971779..34027390
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017595986.3 → XP_017451475.1  protein turtle homolog B isoform X2

    UniProtKB/Swiss-Prot
    D3ZB51

  2. XM_006242743.5 → XP_006242805.1  protein turtle homolog B isoform X4

    See identical proteins and their annotated locations for XP_006242805.1

    UniProtKB/Swiss-Prot
    D3ZB51
    Conserved Domains (6) summary
    cd00096
    Location:41 → 115
    Ig; Immunoglobulin domain
    smart00408
    Location:153 → 210
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:426 → 505
    IG_like; Immunoglobulin like
    cd00063
    Location:510 → 605
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:139 → 225
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:442 → 505
    Ig; Immunoglobulin domain

  3. XM_017595988.3 → XP_017451477.1  protein turtle homolog B isoform X3

    UniProtKB/Swiss-Prot
    D3ZB51

  4. XM_017595989.3 → XP_017451478.1  protein turtle homolog B isoform X5

    UniProtKB/Swiss-Prot
    D3ZB51
    Conserved Domains (6) summary
    cd00096
    Location:41 → 115
    Ig; Immunoglobulin domain
    smart00408
    Location:153 → 210
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:426 → 505
    IG_like; Immunoglobulin like
    cd00063
    Location:510 → 605
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:139 → 225
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:442 → 505
    Ig; Immunoglobulin domain

  5. XM_235959.11 → XP_235959.6  protein turtle homolog B isoform X1

    See identical proteins and their annotated locations for XP_235959.6

    UniProtKB/Swiss-Prot
    D3ZB51
    Conserved Domains (6) summary
    cd00096
    Location:41 → 115
    Ig; Immunoglobulin domain
    smart00408
    Location:153 → 210
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:426 → 505
    IG_like; Immunoglobulin like
    cd00063
    Location:510 → 601
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:139 → 225
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:442 → 505
    Ig; Immunoglobulin domain

RNA

  1. XR_005487809.2 RNA Sequence

  2. XR_005487810.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D3ZB51.1 GenPept UniProtKB/Swiss-Prot:D3ZB51

Gene LinkOut

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