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Frmpd3 FERM and PDZ domain containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 315916, updated on 5-Mar-2024

Summary

Official Symbol
Frmpd3provided by RGD
Official Full Name
FERM and PDZ domain containing 3provided by RGD
Primary source
RGD:1563753
See related
Ensembl:ENSRNOG00000065509 AllianceGenome:RGD:1563753
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563753
Summary
Orthologous to human FRMPD3 (FERM and PDZ domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 23.3), Lung (RPKM 4.1) and 2 other tissues See more
Orthologs
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Genomic context

Location:
Xq32
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (108752511..108902393)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (103964168..104113864)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (111689587..111778943)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene nucleoporin 62 C-terminal like Neighboring gene dynein axonemal assembly factor 6 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene phosphoribosyl pyrophosphate synthetase 1 Neighboring gene TSC22 domain family, member 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
FERM and PDZ domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    108752511..108902393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039100596.2XP_038956524.1  FERM and PDZ domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZZJ0
    Related
    ENSRNOP00000084520.1
    Conserved Domains (5) summary
    smart00295
    Location:148367
    B41; Band 4.1 homologues
    PHA03247
    Location:8291293
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:1995
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13183
    Location:363466
    FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
    cd17169
    Location:145237
    FERM_F1_FRMPD3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 3 (FRMPD3)
  2. XM_063280550.1XP_063136620.1  FERM and PDZ domain-containing protein 3 isoform X2

  3. XM_039100600.2XP_038956528.1  FERM and PDZ domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A6HLS1
    Conserved Domains (4) summary
    smart00295
    Location:13232
    B41; Band 4.1 homologues
    PHA03247
    Location:6941158
    PHA03247; large tegument protein UL36; Provisional
    cd13183
    Location:228331
    FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
    cd17169
    Location:10102
    FERM_F1_FRMPD3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 3 (FRMPD3)
  4. XM_039100595.2XP_038956523.1  FERM and PDZ domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZZJ0
    Conserved Domains (5) summary
    smart00295
    Location:148367
    B41; Band 4.1 homologues
    PHA03247
    Location:8291293
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:1995
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13183
    Location:363466
    FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
    cd17169
    Location:145237
    FERM_F1_FRMPD3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 3 (FRMPD3)
  5. XM_039100599.2XP_038956527.1  FERM and PDZ domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A6HLS1
    Conserved Domains (4) summary
    smart00295
    Location:13232
    B41; Band 4.1 homologues
    PHA03247
    Location:6941158
    PHA03247; large tegument protein UL36; Provisional
    cd13183
    Location:228331
    FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
    cd17169
    Location:10102
    FERM_F1_FRMPD3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 3 (FRMPD3)
  6. XM_039100597.2XP_038956525.1  FERM and PDZ domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A6HLS1
    Conserved Domains (4) summary
    smart00295
    Location:13232
    B41; Band 4.1 homologues
    PHA03247
    Location:6941158
    PHA03247; large tegument protein UL36; Provisional
    cd13183
    Location:228331
    FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
    cd17169
    Location:10102
    FERM_F1_FRMPD3; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 3 (FRMPD3)