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Imp4 IMP U3 small nucleolar ribonucleoprotein 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 316317, updated on 5-Mar-2024

Summary

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Official Symbol
Imp4provided by RGD
Official Full Name
IMP U3 small nucleolar ribonucleoprotein 4provided by RGD
Primary source
RGD:1308463
See related
Ensembl:ENSRNOG00000013285 AllianceGenome:RGD:1308463
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
LRRGT00017; RGD1308463
Summary
Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in fibrillar center. Predicted to be part of Mpp10 complex and small-subunit processome. Predicted to be active in nucleolus. Orthologous to human IMP4 (IMP U3 small nucleolar ribonucleoprotein 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 247.1), Kidney (RPKM 197.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Imp4 in Genome Data Viewer
Location:
9q21
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (44150029..44155167)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (36654127..36659265)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (37769959..37775097, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene forkhead box O1 like Neighboring gene uncharacterized LOC120094660 Neighboring gene transfer RNA glutamic acid (anticodon UUC) 5 Neighboring gene coiled-coil domain containing 115 Neighboring gene protein tyrosine phosphatase, non-receptor type 18 Neighboring gene uncharacterized LOC134480354 Neighboring gene protease, serine, 39

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes. Granneman S, et al. Nucleic Acids Res, 2003 Apr 1. PMID 12655004, Free PMC Article
  2. The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA. Sloan KE, et al. RNA, 2014 Apr. PMID 24550520, Free PMC Article
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC94302

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables rRNA primary transcript binding IEA
Inferred from Electronic Annotation
more info
  
enables snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of Mpp10 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Mpp10 complex ISO
Inferred from Sequence Orthology
more info
  
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
part_of preribosome ISO
Inferred from Sequence Orthology
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
U3 small nucleolar ribonucleoprotein protein IMP4
Names
IMP4 homolog, U3 small nucleolar ribonucleoprotein
IMP4, U3 small nucleolar ribonucleoprotein, homolog
U3 snoRNP protein 4 homolog
U3 snoRNP protein IMP4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009700.1 → NP_001009700.1  U3 small nucleolar ribonucleoprotein protein IMP4

    See identical proteins and their annotated locations for NP_001009700.1

    Status: PROVISIONAL

    Source sequence(s)
    BC087066
    UniProtKB/Swiss-Prot
    Q5PQR5
    UniProtKB/TrEMBL
    A6INA0
    Related
    ENSRNOP00000062237.1, ENSRNOT00000066913.3
    Conserved Domains (1) summary
    smart00879
    Location:86 → 253
    Brix; The Brix domain is found in a number of eukaryotic proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    44150029..44155167
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5PQR5.1 GenPept UniProtKB/Swiss-Prot:Q5PQR5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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