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Tmem104 transmembrane protein 104 [ Mus musculus (house mouse) ]

Gene ID: 320534, updated on 30-Apr-2024

Summary

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Official Symbol
Tmem104provided by MGI
Official Full Name
transmembrane protein 104provided by MGI
Primary source
MGI:MGI:2444222
See related
Ensembl:ENSMUSG00000045980 AllianceGenome:MGI:2444222
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mFLJ00021; C630005D06Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; brainstem; reproductive system; spleen; and trachea. Orthologous to human TMEM104 (transmembrane protein 104). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 13.5), ovary adult (RPKM 10.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Tmem104 in Genome Data Viewer
Location:
11 E2; 11 80.69 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115078313..115137851)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115187487..115247025)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RAB37, member RAS oncogene family Neighboring gene CD300 molecule like family member F Neighboring gene STARR-positive B cell enhancer ABC_E11499 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115019296-115019604 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115024157-115024344 Neighboring gene STARR-positive B cell enhancer ABC_E91 Neighboring gene NHERF family PDZ scaffold protein 1 Neighboring gene STARR-positive B cell enhancer mm9_chr11:115048516-115048817 Neighboring gene N-acetyltransferase 9 (GCN5-related, putative) Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115088135-115088322 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115088428-115088537 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115092913-115093101 Neighboring gene glutamate receptor, ionotropic, NMDA2C (epsilon 3) Neighboring gene STARR-positive B cell enhancer ABC_E44 Neighboring gene ferredoxin reductase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Apr 30. PMID 15449545
  2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 104

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033393.2 → NP_001028565.1  transmembrane protein 104

    Status: VALIDATED

    Source sequence(s)
    AK171457, AL603828, BE948925, BY091433
    Consensus CDS
    CCDS25623.1
    UniProtKB/Swiss-Prot
    Q3TB48, Q3U2Y2
    UniProtKB/TrEMBL
    A2A6S1, B2RU54
    Related
    ENSMUSP00000056805.7, ENSMUST00000061450.7
    Conserved Domains (1) summary
    cl00456
    Location:25 → 444
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    115078313..115137851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156767.1 → XP_036012660.1  transmembrane protein 104 isoform X1

    Conserved Domains (1) summary
    COG0814
    Location:78 → 356
    SdaC; Amino acid permease [Amino acid transport and metabolism]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TB48.1 GenPept UniProtKB/Swiss-Prot:Q3TB48

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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