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Rnase9 ribonuclease, RNase A family, 9 (non-active) [ Mus musculus (house mouse) ]

Gene ID: 328401, updated on 4-May-2024

Summary

Official Symbol
Rnase9provided by MGI
Official Full Name
ribonuclease, RNase A family, 9 (non-active)provided by MGI
Primary source
MGI:MGI:3057273
See related
Ensembl:ENSMUSG00000052382 AllianceGenome:MGI:3057273
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ESRL; Rak1
Summary
Predicted to enable nucleic acid binding activity. Acts upstream of or within positive regulation of flagellated sperm motility involved in capacitation. Predicted to be located in extracellular region. Is expressed in ileum and jejunum. Orthologous to human RNASE9 (ribonuclease A family member 9 (inactive)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 174.4) See more
Orthologs
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Genomic context

See Rnase9 in Genome Data Viewer
Location:
14 C1; 14 26.35 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (51275916..51279360, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (51038459..51041903, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_36663 Neighboring gene predicted gene 8518 Neighboring gene STARR-seq mESC enhancer starr_36664 Neighboring gene ribonuclease, RNase A family, 10 (non-active) Neighboring gene STARR-positive B cell enhancer mm9_chr14:51646418-51646719 Neighboring gene ribonuclease, RNase A family, 11 (non-active) Neighboring gene ribonuclease, RNase A family, 12 (non-active)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (4)  1 citation

General protein information

Preferred Names
inactive ribonuclease-like protein 9
Names
epididymal RNase
ribonuclease A family, member 9
ribonuclease A k1
ribonuclease-like protein 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183032.2NP_898853.2  inactive ribonuclease-like protein 9 precursor

    See identical proteins and their annotated locations for NP_898853.2

    Status: VALIDATED

    Source sequence(s)
    AY303816
    Consensus CDS
    CCDS36909.1
    UniProtKB/Swiss-Prot
    P60154
    UniProtKB/TrEMBL
    Q3KNL9, Q5QJV3
    Related
    ENSMUSP00000066637.4, ENSMUST00000064214.4
    Conserved Domains (1) summary
    cd00163
    Location:57178
    RNase_A; RNase A family, or Pancreatic RNases family; includes vertebrate RNase homologs to the bovine pancreatic ribonuclease A (RNase A). Many of these enzymes have special biological activities; for example, some stimulate the development of vascular ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    51275916..51279360 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519142.4XP_006519205.1  inactive ribonuclease-like protein 9 isoform X1

    See identical proteins and their annotated locations for XP_006519205.1

    UniProtKB/Swiss-Prot
    P60154
    UniProtKB/TrEMBL
    Q3KNL9, Q5QJV3
    Conserved Domains (1) summary
    cd00163
    Location:57178
    RNase_A; RNase A family, or Pancreatic RNases family; includes vertebrate RNase homologs to the bovine pancreatic ribonuclease A (RNase A). Many of these enzymes have special biological activities; for example, some stimulate the development of vascular ...