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IGES immunoglobulin E concentration, serum [ Homo sapiens (human) ]

Gene ID: 3478, updated on 2-Oct-2019

Summary

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Gene symbol
IGES
Gene description
immunoglobulin E concentration, serum
Primary source
MIM:147061
Gene type
unknown
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo

Genomic context

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Location:
5q31.1

Bibliography

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Related articles in PubMed

  1. Thermal sensitivity and flexibility of the Cε3 domains in immunoglobulin E. Doré KA, et al. Biochim Biophys Acta Proteins Proteom, 2017 Nov. PMID 28844738, Free PMC Article
  2. Lupus nephritis: IgE: a regulator of autoimmune inflammation in lupus. Allison SJ. Nat Rev Nephrol, 2014 Dec. PMID 25331788
  3. [Clinical features of atopic asthma and their relation to the T-regulatory cells and total immunoglobulin E]. Liakhovs'ka NV, et al. Lik Sprava, 2014 Mar-Apr. PMID 25286594
  4. Prediagnostic immunoglobulin E levels and risk of chronic lymphocytic leukemia, other lymphomas and multiple myeloma-results of the European Prospective Investigation into Cancer and Nutrition. Nieters A, et al. Carcinogenesis, 2014 Dec. PMID 25269801, Free PMC Article
  5. Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis. Willems S, et al. PLoS One, 2014. PMID 24586471, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Thermal sensitivity and flexibility of the C epsilon3 domains in immunoglobulin E has been reported.
    Title: Thermal sensitivity and flexibility of the Cε3 domains in immunoglobulin E.
  2. The -794 7-CATT locus and the MIF C/7-CATT haplotype were significantly associated with decreased total IgE levels in the plasma, suggesting that these polymorphisms might be a marker for intrinsic atopic dermatitis rather than extrinsic atopic dermatitis.
    Title: Association of Macrophage Migration Inhibitory Factor Polymorphisms with Total Plasma IgE Levels in Patients with Atopic Dermatitis in Korea.
  3. Fecal eosinophil cationic protein was not associated with total serum immunoglobulin E; immunoglobulin E might not be a useful indictor of its sensitization in infancy.
    Title: Faecal eosinophil cationic protein and serum immunoglobulin E in relation to infant feeding practices.
  4. Elevation of plasma-soluble HLA-G in childhood nephrotic syndrome constitutes a risk factor and is associated with IgE.
    Title: Elevation of plasma-soluble HLA-G in childhood nephrotic syndrome is associated with IgE.
  5. The presence of autoreactive IGE increases the probability to develop lupus nephritis.
    Title: Lupus nephritis: IgE: a regulator of autoimmune inflammation in lupus.
  6. Low immunoglobulin E is associated with chronic lymphocytic leukemia, other lymphomas and multiple myeloma.
    Title: Prediagnostic immunoglobulin E levels and risk of chronic lymphocytic leukemia, other lymphomas and multiple myeloma-results of the European Prospective Investigation into Cancer and Nutrition.
  7. Patients with AAAs had significantly higher plasma immunoglobulin E levels than those without abdominal aortic aneurysms.
    Title: IgE actions on CD4+ T cells, mast cells, and macrophages participate in the pathogenesis of experimental abdominal aortic aneurysms.
  8. In patients suffering from carotid artery disease, total IgE, total IgG and oxLDL-IgG levels do not associate with plaque mast cell numbers or other vulnerable plaque histopathological characteristics.
    Title: Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis.
  9. Immunoglobulin E is overexpressed in patients with atopic asthma.
    Title: [Clinical features of atopic asthma and their relation to the T-regulatory cells and total immunoglobulin E].
  10. SNP rs3130941 in the HLA-C region was consistently associated with total IgE levels in 3 independent populations.
    Title: Genome-wide association study for levels of total serum IgE identifies HLA-C in a Japanese population.
Submit: New GeneRIF Correction See all GeneRIFs (14)

Phenotypes

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immunoglobulin E concentration, serum

General gene information

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Property

  • phenotype only

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