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Mal-A3 Maltase A3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35826, updated on 4-Jan-2025

Summary

Official Symbol
Mal-A3provided by FlyBase
Official Full Name
Maltase A3provided by FlyBase
Primary source
FLYBASE:FBgn0002571
Locus tag
Dmel_CG8695
See related
AllianceGenome:FB:FBgn0002571
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8695; Dmel\CG8695; Drome_A3; L; lvpL; LvpL; mal_A3; V
Summary
Predicted to enable alpha-1,4-glucosidase activity. Predicted to be involved in carbohydrate metabolic process. Is expressed in embryonic midgut chamber; embryonic/larval midgut; and organism. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Mal-A3 in Genome Data Viewer
Location:
44D1-44D1; 2-59 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8455909..8457892, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4343414..4345397, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 4e1 Neighboring gene Maltase A1 Neighboring gene Maltase A2 Neighboring gene Maltase A4 Neighboring gene Maltase A5

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables alpha-1,4-glucosidase activity  

General protein information

Preferred Names
maltase A3
Names
CG8695-PA
Mal-A3-PA
gene V
hdl cuticle gene cluster
larval visceral protein L
maltase
NP_476628.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    8455909..8457892 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057280.4 → NP_476628.2  maltase A3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476628.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P07192, Q9V4T8
    Related
    FBpp0087837
    Conserved Domains (2) summary
    cd11328
    Location:22 → 490
    AmyAc_maltase; Alpha amylase catalytic domain found in maltase (also known as alpha glucosidase) and related proteins
    pfam00128
    Location:46 → 400
    Alpha-amylase; Alpha amylase, catalytic domain
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