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Bmerb1 bMERB domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 360459, updated on 5-Mar-2024

Summary

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Official Symbol
Bmerb1provided by RGD
Official Full Name
bMERB domain containing 1provided by RGD
Primary source
RGD:1305733
See related
Ensembl:ENSRNOG00000003198 AllianceGenome:RGD:1305733
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305733
Summary
Predicted to be involved in negative regulation of microtubule depolymerization. Predicted to act upstream of or within negative regulation of cell motility involved in cerebral cortex radial glia guided migration. Predicted to be active in microtubule cytoskeleton. Orthologous to human BMERB1 (bMERB domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 525.3) See more
Orthologs
human mouse all
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Genomic context

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See Bmerb1 in Genome Data Viewer
Location:
10q11
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (2286999..2453890, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (1779834..1946586, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (3411380..3570689)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily C member 1, pseudogene 1 Neighboring gene uncharacterized LOC134480740 Neighboring gene large ribosomal subunit protein uL13-like Neighboring gene meiosis regulator and mRNA stability factor 1 like 1 Neighboring gene nuclear receptor coactivator 4, pseudogene 1 Neighboring gene MPV17 mitochondrial inner membrane protein like Neighboring gene pyridoxal-dependent decarboxylase domain containing 1 Neighboring gene N-terminal asparagine amidase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The newly identified migration inhibitory protein regulates the radial migration in the developing neocortex. Zhang S, et al. Sci Rep, 2014 Aug 7. PMID 25099998, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC109261

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of cell motility involved in cerebral cortex radial glia guided migration ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of microtubule depolymerization ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within negative regulation of cell motility involved in cerebral cortex radial glia guided migration ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of microtubule depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within negative regulation of microtubule depolymerization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
bMERB domain-containing protein 1
Names
uncharacterized protein C16orf45 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014114.1 → NP_001014136.1  bMERB domain-containing protein 1

    See identical proteins and their annotated locations for NP_001014136.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089943
    UniProtKB/Swiss-Prot
    Q5FVJ5
    UniProtKB/TrEMBL
    A6K4E9
    Related
    ENSRNOP00000004346.6, ENSRNOT00000004346.7
    Conserved Domains (1) summary
    cl23748
    Location:63 → 142
    DUF3585; Protein of unknown function (DUF3585)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    2286999..2453890 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086245.2 → XP_038942173.1  bMERB domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    cl23748
    Location:50 → 142
    DUF3585; Protein of unknown function (DUF3585)

  2. XM_063269270.1 → XP_063125340.1  bMERB domain-containing protein 1 isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5FVJ5.1 GenPept UniProtKB/Swiss-Prot:Q5FVJ5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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