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Cep20 centrosomal protein 20 [ Rattus norvegicus (Norway rat) ]

Gene ID: 360461, updated on 5-Mar-2024

Summary

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Official Symbol
Cep20provided by RGD
Official Full Name
centrosomal protein 20provided by RGD
Primary source
RGD:1305823
See related
Ensembl:ENSRNOG00000053230 AllianceGenome:RGD:1305823
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fopnl; RGD1305823
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in cilium assembly. Predicted to be located in centriolar satellite and nucleoplasm. Predicted to be active in centrosome; ciliary basal body; and motile cilium. Orthologous to human CEP20 (centrosomal protein 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 198.2), Muscle (RPKM 148.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
10q11
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (1221294..1243144)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (714051..736826)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (730215..751061)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene aurora kinase A, pseudogene 1 Neighboring gene ATP binding cassette subfamily C member 1 Neighboring gene ribosomal protein S3a, pseudogene 8 Neighboring gene myosin heavy chain 11 Neighboring gene nudE neurodevelopment protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Control of ciliogenesis by FOR20, a novel centrosome and pericentriolar satellite protein. Sedjaï F, et al. J Cell Sci, 2010 Jul 15. PMID 20551181
  2. The sequence and analysis of duplication-rich human chromosome 16. Martin J, et al. Nature, 2004 Dec 23. PMID 15616553
  3. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in microtubule anchoring IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
located_in centriole IEA
Inferred from Electronic Annotation
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
  
is_active_in motile cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in motile cilium ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
centrosomal protein 20
Names
FGFR1OP N-terminal like
lisH domain-containing protein FOPNL

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108261.1 → NP_001101731.1  centrosomal protein 20

    See identical proteins and their annotated locations for NP_001101731.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474126
    UniProtKB/TrEMBL
    A0A0G2JYM1, B0BN31
    Related
    ENSRNOP00000070710.1, ENSRNOT00000083714.2
    Conserved Domains (1) summary
    pfam09398
    Location:43 → 113
    FOP_dimer; FOP N terminal dimerization domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    1221294..1243144
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006245848.5 → XP_006245910.1  centrosomal protein 20 isoform X1

    Conserved Domains (1) summary
    pfam09398
    Location:43 → 113
    FOP_dimer; FOP N terminal dimerization domain

  2. XM_039086246.2 → XP_038942174.1  centrosomal protein 20 isoform X2

    Conserved Domains (1) summary
    cl29685
    Location:43 → 89
    LisH_2

  3. XM_039086247.2 → XP_038942175.1  centrosomal protein 20 isoform X3

    Conserved Domains (1) summary
    cl29685
    Location:43 → 98
    LisH_2
Nucleotide Protein Strain
Heading Accession and Version

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