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Krt28 keratin 28 [ Rattus norvegicus (Norway rat) ]

Gene ID: 360623, updated on 13-Apr-2024

Summary

Official Symbol
Krt28provided by RGD
Official Full Name
keratin 28provided by RGD
Primary source
RGD:1309530
See related
Ensembl:ENSRNOG00000011846 AllianceGenome:RGD:1309530
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ka41; Krt25d
Summary
Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Orthologous to human KRT28 (keratin 28). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 8.7), Brain (RPKM 2.8) and 2 other tissues See more
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Genomic context

See Krt28 in Genome Data Viewer
Location:
10q31
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (84814516..84824857, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (84318352..84328693, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (87276094..87286753, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene keratin 26 Neighboring gene keratin 27 Neighboring gene uncharacterized LOC108352132 Neighboring gene uncharacterized LOC134480872 Neighboring gene keratin 10 Neighboring gene keratin 12

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in hair follicle morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin, type I cytoskeletal 28
Names
keratin 25D
keratin 28, type I
type I keratin KA41

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008760.2NP_001008760.1  keratin, type I cytoskeletal 28 isoform 2

    See identical proteins and their annotated locations for NP_001008760.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    Q6IFW7
    Related
    ENSRNOP00000040950.1, ENSRNOT00000044206.2
    Conserved Domains (1) summary
    pfam00038
    Location:83321
    Filament; Intermediate filament protein
  2. NM_001415700.1NP_001402629.1  keratin, type I cytoskeletal 28 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A8I6ACU5
    Related
    ENSRNOP00000089532.1, ENSRNOT00000106681.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    84814516..84824857 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)