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Suco SUN domain containing ossification factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 360863, updated on 4-Apr-2024

Summary

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Official Symbol
Sucoprovided by RGD
Official Full Name
SUN domain containing ossification factorprovided by RGD
Primary source
RGD:735185
See related
Ensembl:ENSRNOG00000026542 AllianceGenome:RGD:735185
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Dd25
Summary
Predicted to be involved in positive regulation of collagen biosynthetic process; positive regulation of osteoblast differentiation; and regulation of bone remodeling. Predicted to be located in rough endoplasmic reticulum. Predicted to be active in cytoplasm and membrane. Orthologous to human SUCO (SUN domain containing ossification factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 174.6), Spleen (RPKM 156.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Suco in Genome Data Viewer
Location:
13q22
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (76726095..76791174, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (74192808..74257896, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (79736485..79801133, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102553985 Neighboring gene Fas ligand Neighboring gene uncharacterized LOC134481576 Neighboring gene uncharacterized LOC103692015

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Osteopotentia regulates osteoblast maturation, bone formation, and skeletal integrity in mice. Sohaskey ML, et al. J Cell Biol, 2010 May 3. PMID 20440000, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in ossification IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of collagen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of collagen biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of collagen biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of osteoblast differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of osteoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of bone remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of bone remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of bone remodeling ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of bone remodeling ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISO
Inferred from Sequence Orthology
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in rough endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in rough endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in rough endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in rough endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SUN domain-containing ossification factor
Names
SUN-like protein 1
hypothetical protein Dd25
membrane protein CH1
protein C1orf9 homolog
protein osteopotentia homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199403.4 → NP_955435.4  SUN domain-containing ossification factor precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013
    Related
    ENSRNOP00000071346.2, ENSRNOT00000084058.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    76726095..76791174 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063272485.1 → XP_063128555.1  SUN domain-containing ossification factor isoform X6

  2. XM_006250166.5 → XP_006250228.3  SUN domain-containing ossification factor isoform X5

  3. XM_006250164.5 → XP_006250226.3  SUN domain-containing ossification factor isoform X3

  4. XM_008769658.4 → XP_008767880.3  SUN domain-containing ossification factor isoform X4

  5. XM_017598851.3 → XP_017454340.3  SUN domain-containing ossification factor isoform X2

  6. XM_008769657.4 → XP_008767879.3  SUN domain-containing ossification factor isoform X1

  7. XM_039090908.2 → XP_038946836.2  SUN domain-containing ossification factor isoform X7

RNA

  1. XR_010056924.1 RNA Sequence

  2. XR_010056923.1 RNA Sequence

  3. XR_010056925.1 RNA Sequence

  4. XR_001840781.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q710E6.1 GenPept UniProtKB/Swiss-Prot:Q710E6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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