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Heatr3 HEAT repeat containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361375, updated on 5-Mar-2024

Summary

Official Symbol
Heatr3provided by RGD
Official Full Name
HEAT repeat containing 3provided by RGD
Primary source
RGD:1308267
See related
Ensembl:ENSRNOG00000015459 AllianceGenome:RGD:1308267
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308267
Summary
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein import into nucleus and ribosomal large subunit biogenesis. Orthologous to human HEATR3 (HEAT repeat containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 83.4), Heart (RPKM 66.9) and 9 other tissues See more
Orthologs
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Genomic context

See Heatr3 in Genome Data Viewer
Location:
19p11
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (35065915..35103779, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (18892477..18930502, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (19858419..19896782, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene adenylate cyclase 7 Neighboring gene uncharacterized LOC134483299 Neighboring gene terminal nucleotidyltransferase 4B Neighboring gene uncharacterized LOC134483300 Neighboring gene uncharacterized LOC108348906 Neighboring gene CTD nuclear envelope phosphatase 1 regulatory subunit 1 Neighboring gene mRNA turnover 4, ribosome maturation factor, pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in erythrocyte maturation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein import into nucleus ISO
Inferred from Sequence Orthology
more info
 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ribosomal large subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
HEAT repeat-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    35065915..35103779 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_341654.10XP_341655.3  HEAT repeat-containing protein 3

    See identical proteins and their annotated locations for XP_341655.3

    UniProtKB/TrEMBL
    D3ZV81
    Related
    ENSRNOP00000020793.5
    Conserved Domains (2) summary
    cd13394
    Location:2675
    Syo1_like; Fungal symportin 1 (syo1) and similar proteins
    sd00043
    Location:3565
    ARM; armadillo repeat [structural motif]