U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp52 zinc finger protein 52 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361487, updated on 2-May-2024

Summary

Go to the top of the page Help
Symbol
Zfp52provided by RGD
Full Name
zinc finger protein 52provided by RGD
Primary source
RGD:1359149
See related
Ensembl:ENSRNOG00000042826 AllianceGenome:RGD:1359149
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Orthologous to human ZNF876P (zinc finger protein 876, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 121.4), Thymus (RPKM 45.1) and 9 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
1q12
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (69998534..70036017)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (61326960..61363105)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (61389594..61426327)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 54-like Neighboring gene transfer RNA arginine (anticodon CCU) 1 Neighboring gene ribonuclease H2, subunit B, pseudogene 1 Neighboring gene zinc finger protein 53 Neighboring gene uncharacterized LOC102547319 Neighboring gene uncharacterized LOC134482874 Neighboring gene zinc finger protein 948 Neighboring gene zinc finger protein 420-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 52
Names
zinc finger protein 695-like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014158.1 → NP_001014180.1  zinc finger protein 52

    See identical proteins and their annotated locations for NP_001014180.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085827
    UniProtKB/TrEMBL
    Q5U2X3
    Related
    ENSRNOP00000044868.3, ENSRNOT00000050119.6
    Conserved Domains (6) summary
    COG5048
    Location:329 → 702
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:241 → 324
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:667 → 687
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:443 → 463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:44 → 84
    KRAB; KRAB box
    pfam13465
    Location:707 → 730
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    69998534..70036017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063266251.1 → XP_063122321.1  zinc finger protein 52 isoform X1

    UniProtKB/TrEMBL
    Q5U2X3

  2. XM_063266237.1 → XP_063122307.1  zinc finger protein 52 isoform X1

    UniProtKB/TrEMBL
    Q5U2X3

  3. XM_017589343.3 → XP_017444832.1  zinc finger protein 52 isoform X1

    UniProtKB/TrEMBL
    Q5U2X3
    Conserved Domains (6) summary
    COG5048
    Location:329 → 702
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:241 → 324
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:667 → 687
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:443 → 463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:44 → 84
    KRAB; KRAB box
    pfam13465
    Location:707 → 730
    zf-H2C2_2; Zinc-finger double domain

  4. XM_039081352.2 → XP_038937280.1  zinc finger protein 52 isoform X2

    Conserved Domains (6) summary
    COG5048
    Location:297 → 670
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:209 → 292
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:635 → 655
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:411 → 431
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:675 → 698
    zf-H2C2_2; Zinc-finger double domain

  5. XM_039081334.2 → XP_038937262.1  zinc finger protein 52 isoform X1

    UniProtKB/TrEMBL
    Q5U2X3
    Conserved Domains (6) summary
    COG5048
    Location:329 → 702
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:241 → 324
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:667 → 687
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:443 → 463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:44 → 84
    KRAB; KRAB box
    pfam13465
    Location:707 → 730
    zf-H2C2_2; Zinc-finger double domain

  6. XM_039081333.2 → XP_038937261.1  zinc finger protein 52 isoform X1

    UniProtKB/TrEMBL
    Q5U2X3
    Conserved Domains (6) summary
    COG5048
    Location:329 → 702
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:241 → 324
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:667 → 687
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:443 → 463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:44 → 84
    KRAB; KRAB box
    pfam13465
    Location:707 → 730
    zf-H2C2_2; Zinc-finger double domain

  7. XM_039081349.2 → XP_038937277.1  zinc finger protein 52 isoform X1

    UniProtKB/TrEMBL
    Q5U2X3
    Conserved Domains (6) summary
    COG5048
    Location:329 → 702
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:241 → 324
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:667 → 687
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:443 → 463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:44 → 84
    KRAB; KRAB box
    pfam13465
    Location:707 → 730
    zf-H2C2_2; Zinc-finger double domain

  8. XM_017589345.3 → XP_017444834.1  zinc finger protein 52 isoform X1

    UniProtKB/TrEMBL
    Q5U2X3
    Conserved Domains (6) summary
    COG5048
    Location:329 → 702
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:241 → 324
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:667 → 687
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:443 → 463
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:44 → 84
    KRAB; KRAB box
    pfam13465
    Location:707 → 730
    zf-H2C2_2; Zinc-finger double domain

  9. XM_039081361.2 → XP_038937289.1  zinc finger protein 52 isoform X2

    Related
    ENSRNOP00000094976.1
    Conserved Domains (6) summary
    COG5048
    Location:297 → 670
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:209 → 292
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:635 → 655
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:411 → 431
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
    pfam13465
    Location:675 → 698
    zf-H2C2_2; Zinc-finger double domain

  10. XM_063266243.1 → XP_063122313.1  zinc finger protein 52 isoform X1

    UniProtKB/TrEMBL
    Q5U2X3
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous