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Tmem134 transmembrane protein 134 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361695, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem134provided by RGD
Official Full Name
transmembrane protein 134provided by RGD
Primary source
RGD:1305824
See related
Ensembl:ENSRNOG00000022153 AllianceGenome:RGD:1305824
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305824
Summary
Predicted to be located in cytosol and perinuclear region of cytoplasm. Orthologous to human TMEM134 (transmembrane protein 134). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 193.8), Muscle (RPKM 180.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tmem134 in Genome Data Viewer
Location:
1q43
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (210848761..210857735)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (201419225..201424778)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (219374005..219383365)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol transfer protein, membrane-associated 1 Neighboring gene aryl-hydrocarbon receptor-interacting protein Neighboring gene calcium binding protein 4 Neighboring gene G protein-coupled receptor 152 Neighboring gene ribosomal protein L35A, pseudogene 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Systematic identification of hepatitis E virus ORF2 interactome reveals that TMEM134 engages in ORF2-mediated NF-κB pathway. Tian Y, et al. Virus Res, 2017 Jan 15. PMID 27899274
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
transmembrane protein 134

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001078647.1 → NP_001072115.1  transmembrane protein 134 isoform a

    See identical proteins and their annotated locations for NP_001072115.1

    Status: VALIDATED

    Source sequence(s)
    AW434905, BP495609, BQ190138
    UniProtKB/TrEMBL
    A0A8I6A5Q3, A6HYT7, D3ZF56
    Related
    ENSRNOP00000031381.4, ENSRNOT00000030340.7
    Conserved Domains (1) summary
    pfam05915
    Location:57 → 193
    DUF872; Eukaryotic protein of unknown function (DUF872)

  2. NM_001078648.1 → NP_001072116.1  transmembrane protein 134 isoform b

    See identical proteins and their annotated locations for NP_001072116.1

    Status: VALIDATED

    Source sequence(s)
    BI278839, BP495609
    UniProtKB/TrEMBL
    A0A8I6A5Q3, A6HYT8, D4A3S9
    Related
    ENSRNOP00000035615.2, ENSRNOT00000030324.3
    Conserved Domains (1) summary
    pfam05915
    Location:57 → 178
    DUF872; Eukaryotic protein of unknown function (DUF872)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    210848761..210857735
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063268167.1 → XP_063124237.1  transmembrane protein 134 isoform X5

  2. XM_063268169.1 → XP_063124239.1  transmembrane protein 134 isoform X7

  3. XM_039083754.2 → XP_038939682.1  transmembrane protein 134 isoform X2

    UniProtKB/TrEMBL
    A0A8I6A5Q3
    Related
    ENSRNOP00000088050.1
    Conserved Domains (1) summary
    pfam05915
    Location:57 → 168
    DUF872; Eukaryotic protein of unknown function (DUF872)

  4. XM_039083761.2 → XP_038939689.1  transmembrane protein 134 isoform X6

    UniProtKB/TrEMBL
    A0A8I6A5Q3
    Conserved Domains (1) summary
    pfam05915
    Location:57 → 153
    DUF872; Eukaryotic protein of unknown function (DUF872)

  5. XM_039083743.2 → XP_038939671.1  transmembrane protein 134 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A5Q3, A6HYT9
    Conserved Domains (1) summary
    pfam05915
    Location:57 → 184
    DUF872; Eukaryotic protein of unknown function (DUF872)

  6. XM_063268164.1 → XP_063124234.1  transmembrane protein 134 isoform X3

  7. XM_063268165.1 → XP_063124235.1  transmembrane protein 134 isoform X4

  8. XM_063268170.1 → XP_063124240.1  transmembrane protein 134 isoform X9

  9. XM_039083773.2 → XP_038939701.1  transmembrane protein 134 isoform X10

  10. XM_039083764.2 → XP_038939692.1  transmembrane protein 134 isoform X8

    Conserved Domains (1) summary
    pfam05915
    Location:5 → 109
    DUF872; Eukaryotic protein of unknown function (DUF872)
Nucleotide Protein Strain
Heading Accession and Version

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