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Ybey ybeY metalloendoribonuclease [ Rattus norvegicus (Norway rat) ]

Gene ID: 361822, updated on 5-Mar-2024

Summary

Official Symbol
Ybeyprovided by RGD
Official Full Name
ybeY metalloendoribonucleaseprovided by RGD
Primary source
RGD:1308722
See related
Ensembl:ENSRNOG00000021365 AllianceGenome:RGD:1308722
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308722
Summary
Predicted to enable endoribonuclease activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic; proteolysis; and rRNA processing. Predicted to be located in nucleus. Orthologous to human YBEY (ybeY metalloendoribonuclease). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 20.8), Lung (RPKM 18.1) and 9 other tissues See more
Orthologs
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Genomic context

See Ybey in Genome Data Viewer
Location:
20p12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (12164678..12175150)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (12165192..12174713)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (12917111..12926587)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene lanosterol synthase Neighboring gene minichromosome maintenance complex component 3 associated protein Neighboring gene similar to human chromosome 21 open reading frame 58 Neighboring gene pericentrin Neighboring gene uncharacterized LOC134483886 Neighboring gene disco-interacting protein 2 homolog A Neighboring gene S100 calcium binding protein B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA endonuclease activity ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
endoribonuclease YbeY
Names
putative ribonuclease
rRNA maturation factor homolog
ybeY metallopeptidase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108529.1NP_001101999.1  endoribonuclease YbeY

    See identical proteins and their annotated locations for NP_001101999.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473988
    UniProtKB/TrEMBL
    A6JKD1, D4A815
    Related
    ENSRNOP00000030496.4, ENSRNOT00000038953.5
    Conserved Domains (1) summary
    TIGR00043
    Location:35148
    TIGR00043; rRNA maturation RNase YbeY

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    12164678..12175150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063279233.1XP_063135303.1  endoribonuclease YbeY isoform X2

  2. XM_006256301.5XP_006256363.1  endoribonuclease YbeY isoform X1

    See identical proteins and their annotated locations for XP_006256363.1

    UniProtKB/TrEMBL
    A6JKD1, D4A815
    Conserved Domains (1) summary
    TIGR00043
    Location:35148
    TIGR00043; rRNA maturation RNase YbeY