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Ns5atp4 NS5A transactivated protein 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361985, updated on 13-Apr-2024

Summary

Official Symbol
Ns5atp4provided by RGD
Official Full Name
NS5A transactivated protein 4provided by RGD
Primary source
RGD:1359625
See related
Ensembl:ENSRNOG00000017758 AllianceGenome:RGD:1359625
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in phagocytosis. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in Golgi apparatus and mitochondrion. Orthologous to human C1orf43 (chromosome 1 open reading frame 43). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 463.7), Muscle (RPKM 427.7) and 9 other tissues See more
Orthologs
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Genomic context

See Ns5atp4 in Genome Data Viewer
Location:
2q34
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (177792070..177804943)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (175494406..175507281)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (189400696..189413614)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691621 Neighboring gene HCLS1 associated protein X-1 Neighboring gene ubiquitin associated protein 2-like Neighboring gene cilia and flagella associated protein 141 Neighboring gene microRNA 190b Neighboring gene tropomyosin 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC112629, MGC124898

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within in utero embryonic development ISO
Inferred from Sequence Orthology
more info
 
involved_in phagocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phagocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in phagocytosis ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
protein C1orf43 homolog
Names
NS5A (hepatitis C virus) transactivated protein 4 like 1
NS5A transactivated protein 4 like 1
uncharacterized protein C1orf43 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014174.3NP_001014196.1  protein C1orf43 homolog isoform 2

    See identical proteins and their annotated locations for NP_001014196.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/Swiss-Prot
    Q5XII8
    UniProtKB/TrEMBL
    A6J6J2
    Related
    ENSRNOP00000046713.3, ENSRNOT00000046919.6
    Conserved Domains (1) summary
    pfam07406
    Location:6170
    NICE-3; NICE-3 protein
  2. NM_001413650.1NP_001400579.1  protein C1orf43 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I6GL14, A6J6J1, Q4KMA3
    Related
    ENSRNOP00000095163.1, ENSRNOT00000100523.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    177792070..177804943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)