U.S. flag

An official website of the United States government

Sod3 Superoxide dismutase 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36232, updated on 4-Jan-2025

Summary

Official Symbol
Sod3provided by FlyBase
Official Full Name
Superoxide dismutase 3provided by FlyBase
Primary source
FLYBASE:FBgn0033631
Locus tag
Dmel_CG9027
See related
AllianceGenome:FB:FBgn0033631
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13200; CG9027; CT25938; Dmel/CG9027; Dmel\CG9027; dSod3; dSOD3; sod-3; SOD3
Summary
Enables superoxide dismutase activity. Involved in UV protection and removal of superoxide radicals. Located in extracellular space. Is expressed in anterior midgut primordium; organism; and posterior midgut primordium. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; artery disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Sod3 in Genome Data Viewer
Location:
47F7-47F8; 2-64 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11380347..11384114, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7267852..7271619, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Tetraspanin 47F Neighboring gene sprite Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Threonine-TGT 2-1

Genomic regions, transcripts, and products

Bibliography

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables copper ion binding  
enables copper ion binding  
enables superoxide dismutase activity  
enables superoxide dismutase activity PubMed 
enables superoxide dismutase activity PubMed 
Component Evidence Code Pubs
located_in extracellular space PubMed 
located_in plasma membrane PubMed 

General protein information

Preferred Names
superoxide dismutase 3
Names
CG9027-PA
CG9027-PB
CG9027-PD
CG9027-PE
CG9027-PF
Sod3-PA
Sod3-PB
Sod3-PD
Sod3-PE
Sod3-PF
NP_001033939.2
NP_001036536.1
NP_001303344.1
NP_610682.2
NP_725046.2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    11380347..11384114 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001043071.2 → NP_001036536.1  superoxide dismutase 3, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036536.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JR71
    Conserved Domains (1) summary
    pfam00080
    Location:42 → 178
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)
  2. NM_001038850.2 → NP_001033939.2  superoxide dismutase 3, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033939.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8K9
    Conserved Domains (1) summary
    pfam00080
    Location:43 → 178
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)
  3. NM_001316415.1 → NP_001303344.1  superoxide dismutase 3, isoform F [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D8FT33, Q0E9C3, Q5U195, Q7JR71, Q95T42
    Conserved Domains (1) summary
    pfam00080
    Location:38 → 178
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)
  4. NM_165829.3 → NP_725046.2  superoxide dismutase 3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725046.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D8FT33, Q0E9C3, Q5U195, Q7JR71, Q95T42
    Related
    FBpp0088877
    Conserved Domains (1) summary
    pfam00080
    Location:38 → 178
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)
  5. NM_136838.3 → NP_610682.2  superoxide dismutase 3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610682.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D8FT33, Q0E9C3, Q5U195, Q7JR71, Q95T42
    Related
    FBpp0088878
    Conserved Domains (1) summary
    pfam00080
    Location:38 → 178
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)
External link. Please review our privacy policy.