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Gpatch11 G patch domain containing 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362685, updated on 30-Mar-2024

Summary

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Official Symbol
Gpatch11provided by RGD
Official Full Name
G patch domain containing 11provided by RGD
Primary source
RGD:1311424
See related
Ensembl:ENSRNOG00000025317 AllianceGenome:RGD:1311424
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ccdc75; RGD1311424
Summary
Predicted to enable nucleic acid binding activity. Predicted to be active in kinetochore. Orthologous to human GPATCH11 (G-patch domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 65.5), Brain (RPKM 64.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gpatch11 in Genome Data Viewer
Location:
6q12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (21982074..21995562, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (16229933..16243305, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (1410461..1421506)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene keratin-associated protein 5-1-like Neighboring gene sulfotransferase family 6B member 1 Neighboring gene uncharacterized LOC120103477 Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 2 Neighboring gene HEAT repeat containing 5B Neighboring gene striatin Neighboring gene vitrin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Ohta S, et al. Cell, 2010 Sep 3. PMID 20813266, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
G patch domain-containing protein 11
Names
coiled-coil domain containing 75
coiled-coil domain-containing protein 75

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108700.2 → NP_001102170.1  G patch domain-containing protein 11

    See identical proteins and their annotated locations for NP_001102170.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A6H9V4, F1LV52
    Related
    ENSRNOP00000031805.6, ENSRNOT00000034919.6
    Conserved Domains (2) summary
    pfam01585
    Location:70 → 113
    G-patch; G-patch domain
    pfam13821
    Location:212 → 259
    DUF4187; Domain of unknown function (DUF4187)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    21982074..21995562 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039112453.2 → XP_038968381.1  G patch domain-containing protein 11 isoform X2

    UniProtKB/TrEMBL
    A6H9V4, F1LV52
    Conserved Domains (2) summary
    pfam01585
    Location:70 → 113
    G-patch; G-patch domain
    pfam13821
    Location:212 → 259
    DUF4187; Domain of unknown function (DUF4187)

  2. XM_006239636.5 → XP_006239698.1  G patch domain-containing protein 11 isoform X2

    See identical proteins and their annotated locations for XP_006239698.1

    UniProtKB/TrEMBL
    A6H9V4, F1LV52
    Conserved Domains (2) summary
    pfam01585
    Location:70 → 113
    G-patch; G-patch domain
    pfam13821
    Location:212 → 259
    DUF4187; Domain of unknown function (DUF4187)

  3. XM_063262044.1 → XP_063118114.1  G patch domain-containing protein 11 isoform X1

RNA

  1. XR_010052099.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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