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Adck5 aarF domain containing kinase 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362943, updated on 30-Mar-2024

Summary

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Official Symbol
Adck5provided by RGD
Official Full Name
aarF domain containing kinase 5provided by RGD
Primary source
RGD:1305504
See related
Ensembl:ENSRNOG00000030334 AllianceGenome:RGD:1305504
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be integral component of membrane. Orthologous to human ADCK5 (aarF domain containing kinase 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 267.9), Liver (RPKM 139.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Adck5 in Genome Data Viewer
Location:
7q34
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (110182275..110200088)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (108301623..108319439)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117643976..117661789)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479929 Neighboring gene uncharacterized LOC134479928 Neighboring gene cleavage and polyadenylation specific factor 1 Neighboring gene solute carrier family 39 member 4 Neighboring gene VPS28 subunit of ESCRT-I

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC112651, MGC188570

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized aarF domain-containing protein kinase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135798.2 → NP_001129270.1  uncharacterized aarF domain-containing protein kinase 5

    See identical proteins and their annotated locations for NP_001129270.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    A6HSB0, G3V9I7
    Related
    ENSRNOP00000048745.5, ENSRNOT00000044893.5
    Conserved Domains (2) summary
    COG0661
    Location:128 → 499
    AarF; Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme transport and metabolism, Signal transduction mechanisms]
    cd13969
    Location:169 → 420
    ADCK1-like; aarF domain containing kinase 1 and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    110182275..110200088
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079556.2 → XP_038935484.1  uncharacterized aarF domain-containing protein kinase 5 isoform X1

    Conserved Domains (1) summary
    cd13969
    Location:62 → 313
    ADCK1-like; aarF domain containing kinase 1 and similar proteins

  2. XM_039079558.2 → XP_038935486.1  uncharacterized aarF domain-containing protein kinase 5 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:1 → 166
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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