U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pdcd7 programmed cell death 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363082, updated on 30-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Pdcd7provided by RGD
Official Full Name
programmed cell death 7provided by RGD
Primary source
RGD:1308961
See related
Ensembl:ENSRNOG00000014340 AllianceGenome:RGD:1308961
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in response to glucocorticoid. Predicted to act upstream of or within positive regulation of T cell apoptotic process and positive regulation of apoptotic signaling pathway. Predicted to be part of U12-type spliceosomal complex. Orthologous to human PDCD7 (programmed cell death 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 153.4), Lung (RPKM 144.1) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
8q24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (74757768..74772495)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (65862606..65877333)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (70860671..70875471)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene cartilage intermediate layer protein Neighboring gene caseinolytic mitochondrial matrix peptidase chaperone subunit X Neighboring gene ubiquitin associated protein 1-like Neighboring gene kelch repeat and BTB domain containing 13

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Characterization of a novel mouse cDNA, ES18, involved in apoptotic cell death of T-cells. Park EJ, et al. Nucleic Acids Res, 1999 Mar 15. PMID 10037816, Free PMC Article
  2. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. Will CL, et al. RNA, 2004 Jun. PMID 15146077, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of T cell apoptotic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within positive regulation of apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in response to glucocorticoid ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of U12-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U12-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
programmed cell death protein 7

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395644.1 → NP_001382573.1  programmed cell death protein 7

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    D4ACM6
    Related
    ENSRNOP00000019258.6, ENSRNOT00000019258.7
    Conserved Domains (1) summary
    pfam16021
    Location:194 → 482
    PDCD7; Programmed cell death protein 7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    74757768..74772495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001108768.1: Suppressed sequence

    Description
    NM_001108768.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous