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Gemin8 gem (nuclear organelle) associated protein 8 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363462, updated on 5-Mar-2024

Summary

Official Symbol
Gemin8provided by RGD
Official Full Name
gem (nuclear organelle) associated protein 8provided by RGD
Primary source
RGD:1359160
See related
Ensembl:ENSRNOG00000029038 AllianceGenome:RGD:1359160
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam51a1
Summary
Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in cytosol and nucleus. Predicted to be part of SMN complex. Orthologous to human GEMIN8 (gem nuclear organelle associated protein 8). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 68.0), Brain (RPKM 66.5) and 9 other tissues See more
Orthologs
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Genomic context

See Gemin8 in Genome Data Viewer
Location:
Xq14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (31891446..31910280, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (28259806..28278641, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (29806605..29825439, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 2 Neighboring gene Ofd1 centriole and centriolar satellite protein Neighboring gene glycoprotein m6b Neighboring gene glycine receptor, alpha 2 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 4, pseudogene 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC94189

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in spliceosomal snRNP assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in spliceosomal snRNP assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of SMN complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of SMN complex ISO
Inferred from Sequence Orthology
more info
 
part_of SMN-Sm protein complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
gem-associated protein 8
Names
family with sequence similarity 51, member A1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007756.1NP_001007757.1  gem-associated protein 8

    See identical proteins and their annotated locations for NP_001007757.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079160
    UniProtKB/TrEMBL
    Q6AY77
    Related
    ENSRNOP00000044281.3, ENSRNOT00000048155.5
    Conserved Domains (1) summary
    pfam15348
    Location:10239
    GEMIN8; Gemini of Cajal bodies-associated protein 8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    31891446..31910280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)