Gjd3 gap junction protein, delta 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gjd3provided by RGD
Official Full Name: gap junction protein, delta 3provided by RGD
Primary source: RGD:1308942
See related: Ensembl:ENSRNOG00000051691 AllianceGenome:RGD:1308942
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Cxnr; Gjc1; Cx30.2
Summary: Enables gap junction channel activity. Involved in response to glucose. Predicted to be located in cell surface and gap junction. Predicted to be part of connexin complex. Orthologous to human GJD3 (gap junction protein delta 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 5.5), Brain (RPKM 4.4) and 8 other tissues See more
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (84429923..84432011, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (83933694..83935759, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (86888982..86891915, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables gap junction channel activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	IBA Inferred from Biological aspect of Ancestor more info
enables gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	ISO Inferred from Sequence Orthology more info
enables monoatomic ion channel activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
NOT involved_in AV node cell to bundle of His cell communication by electrical coupling	ISO Inferred from Sequence Orthology more info
involved_in AV node cell to bundle of His cell communication by electrical coupling	ISO Inferred from Sequence Orthology more info
NOT involved_in cell communication involved in cardiac conduction	ISO Inferred from Sequence Orthology more info
involved_in cell-cell signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in gap junction assembly	ISO Inferred from Sequence Orthology more info
involved_in monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within monoatomic ion transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of cardiac conduction	ISO Inferred from Sequence Orthology more info
NOT involved_in negative regulation of cell communication by electrical coupling involved in cardiac conduction	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of cell communication by electrical coupling involved in cardiac conduction	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of heart rate	ISO Inferred from Sequence Orthology more info
involved_in response to glucose	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cell surface	ISO Inferred from Sequence Orthology more info
part_of connexin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of connexin complex	ISO Inferred from Sequence Orthology more info
located_in gap junction	ISO Inferred from Sequence Orthology more info