Tecrl trans-2,3-enoyl-CoA reductase-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tecrlprovided by RGD
Official Full Name: trans-2,3-enoyl-CoA reductase-likeprovided by RGD
Primary source: RGD:1304608
See related: Ensembl:ENSRNOG00000001912 AllianceGenome:RGD:1304608
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Srd5a2l2
Summary: Predicted to enable oxidoreductase activity. Predicted to be involved in very long-chain fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 3. Orthologous to human TECRL (trans-2,3-enoyl-CoA reductase like). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 554.3) See more
Orthologs: human mouse all
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Genomic context

Location:: 14p21

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (25086930..25159957)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (24732241..24805272)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (26662851..26735878)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables oxidoreductase activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity, acting on the CH-CH group of donors	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in very long-chain fatty acid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: trans-2,3-enoyl-CoA reductase-like

Names: steroid 5 alpha-reductase 2-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108860.1 → NP_001102330.1 trans-2,3-enoyl-CoA reductase-like

See identical proteins and their annotated locations for NP_001102330.1

Status: PROVISIONAL

Source sequence(s)

CH473981

UniProtKB/TrEMBL

A6JCS7, A6JCS8, D4A1Y9

Related

ENSRNOP00000002621.4, ENSRNOT00000002621.6

Conserved Domains (3) summary

PLN02560
Location:77 → 361

PLN02560; enoyl-CoA reductase

cl00155
Location:60 → 135

UBQ; Ubiquitin-like proteins

cl21511
Location:210 → 361

PEMT; Phospholipid methyltransferase