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Arl11 ADP-ribosylation factor like GTPase 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 364396, updated on 5-Mar-2024

Summary

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Official Symbol
Arl11provided by RGD
Official Full Name
ADP-ribosylation factor like GTPase 11provided by RGD
Primary source
RGD:1308083
See related
Ensembl:ENSRNOG00000014653 AllianceGenome:RGD:1308083
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human ARL11 (ADP ribosylation factor like GTPase 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 41.7), Lung (RPKM 32.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Arl11 in Genome Data Viewer
Location:
15p12
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (39659404..39661651)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (35483330..35485579)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (41639985..41645685)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097004 Neighboring gene uncharacterized LOC120097165 Neighboring gene EBP like Neighboring gene karyopherin subunit alpha 3 Neighboring gene ribosomal protein S20, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC108833

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within hematopoietic progenitor cell differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ADP-ribosylation factor-like protein 11
Names
ADP-ribosylation factor-like 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013433.1 → NP_001013451.1  ADP-ribosylation factor-like protein 11

    See identical proteins and their annotated locations for NP_001013451.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091183
    UniProtKB/Swiss-Prot
    Q5BK71
    UniProtKB/TrEMBL
    A6K6B5
    Related
    ENSRNOP00000019646.2, ENSRNOT00000019646.4
    Conserved Domains (2) summary
    pfam00071
    Location:13 → 172
    Ras; Ras family
    cl21455
    Location:12 → 167
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    39659404..39661651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017599762.3 → XP_017455251.1  ADP-ribosylation factor-like protein 11 isoform X1

    UniProtKB/Swiss-Prot
    Q5BK71
    UniProtKB/TrEMBL
    A6K6B5
    Related
    ENSRNOP00000096153.1
    Conserved Domains (2) summary
    pfam00071
    Location:13 → 172
    Ras; Ras family
    cl21455
    Location:12 → 167
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BK71.1 GenPept UniProtKB/Swiss-Prot:Q5BK71

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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