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Xrra1 X-ray radiation resistance associated 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 365313, updated on 5-Mar-2024

Summary

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Official Symbol
Xrra1provided by RGD
Official Full Name
X-ray radiation resistance associated 1provided by RGD
Primary source
RGD:1305502
See related
Ensembl:ENSRNOG00000026503 AllianceGenome:RGD:1305502
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in response to X-ray. Predicted to be located in cytoplasm and nuclear body. Predicted to be active in nucleus. Orthologous to human XRRA1 (X-ray radiation resistance associated 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 62.8), Thymus (RPKM 42.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Xrra1 in Genome Data Viewer
Location:
1q32
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (163595403..163660003)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (154183330..154247883)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (164849833..164917570)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483763 Neighboring gene signal peptidase complex subunit 2 Neighboring gene uncharacterized LOC102547456 Neighboring gene ring finger protein 169 Neighboring gene small nucleolar RNA SNORA20 Neighboring gene Set nuclear proto-oncogene, pseudogene 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis. Mesak FM, et al. BMC Genomics, 2003 Aug 9. PMID 12908878, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in response to X-ray ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
X-ray radiation resistance-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    163595403..163660003
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003748930.6 → XP_003748978.1  X-ray radiation resistance-associated protein 1 isoform X1

    See identical proteins and their annotated locations for XP_003748978.1

    UniProtKB/TrEMBL
    A0A0G2K0N1
    Related
    ENSRNOP00000071512.1
    Conserved Domains (3) summary
    cd00116
    Location:139 → 270
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:147 → 169
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:192 → 270
    LRR_8; Leucine rich repeat

  2. XM_006229821.5 → XP_006229883.1  X-ray radiation resistance-associated protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006229883.1

    Conserved Domains (3) summary
    cd00116
    Location:96 → 227
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:104 → 126
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:149 → 227
    LRR_8; Leucine rich repeat

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001113753.1: Suppressed sequence

    Description
    NM_001113753.1: This RefSeq was temporarily suppressed because the CDS was partial.
Nucleotide Protein Strain
Heading Accession and Version

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