H2ac18 H2A clustered histone 18 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: H2ac18provided by RGD
Official Full Name: H2A clustered histone 18provided by RGD
Primary source: RGD:1307165
See related: AllianceGenome:RGD:1307165
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: H2A.2; Hist2h2aa; Hist2h2aa1; Hist2h2aa3
Summary: Predicted to enable DNA binding activity. Predicted to be involved in heterochromatin assembly. Predicted to be located in nucleus. Predicted to be part of nucleosome. Orthologous to several human genes including H2AC19 (H2A clustered histone 19). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 2q34

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (186497271..186497865)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (183808398..183808992)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (198388766..198389293)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables nucleosomal DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info
enables structural constituent of chromatin	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in heterochromatin formation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of nucleosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: histone H2A type 1

Names: histone 2, H2aa; histone cluster 2 H2A family member A3; histone cluster 2, H2aa; histone cluster 2, H2aa1; histone cluster 2, H2aa3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001315493.3 → NP_001302422.1 histone H2A type 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000002

UniProtKB/Swiss-Prot

P0CC09, Q64598

UniProtKB/TrEMBL

K7S2S2

Conserved Domains (1) summary

PTZ00017
Location:1 → 130

PTZ00017; histone H2A; Provisional