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Act79B Actin 79B [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40444, updated on 10-May-2024

Summary

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Official Symbol
Act79Bprovided by FlyBase
Official Full Name
Actin 79Bprovided by FlyBase
Primary source
FLYBASE:FBgn0000045
Locus tag
Dmel_CG7478
See related
AllianceGenome:FB:FBgn0000045
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
143060_f_at; act 79B; ACT4; act79B; actin; Actin; ArpF; CG7478; D; Dmel\CG7478; mus79B
Summary
Predicted to be involved in mitotic cytokinesis. Is expressed in adult circulatory system; adult head; adult somatic muscle cell; male-specific anatomical entity; and tubular muscle cell. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome and autosomal dominant nonsyndromic deafness 20. Orthologous to human ACTB (actin beta) and ACTG1 (actin gamma 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Act79B in Genome Data Viewer
Location:
79A6-79A6; 3-47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21985210..21987190)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21978310..21980290)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Chitin synthase 2 Neighboring gene Delta[1]-pyrroline-5-carboxylate synthase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Developmental expression of a Drosophila actin gene encoding actin I. Zulauf E, et al. Nature, 1981 Aug 6. PMID 6789212
  2. TORC1 regulation of dendrite regrowth after pruning is linked to actin and exocytosis. Sanal N, et al. PLoS Genet, 2023 May. PMID 37167328, Free PMC Article
  3. Evolution of a neuromuscular sexual dimorphism in the Drosophila montium species group. Liang HQ, et al. Sci Rep, 2021 Jul 27. PMID 34315982, Free PMC Article
  4. Absence of the Drosophila jump muscle actin Act79B is compensated by up-regulation of Act88F. Dohn TE, et al. Dev Dyn, 2018 Apr. PMID 29318731, Free PMC Article
  5. Reassessment of 79B actin gene expression in the abdomen of adult Drosophila melanogaster. Ohshima S, et al. Insect Mol Biol, 1997 Aug. PMID 9272440

See all (147) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling.
    Title: Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling.
  2. TORC1 regulation of dendrite regrowth after pruning is linked to actin and exocytosis.
    Title: TORC1 regulation of dendrite regrowth after pruning is linked to actin and exocytosis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mitotic cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
actin 79B
Names
79B actin
Act79B-PA
Act79B-PB
CG7478-PA
CG7478-PB
F-actin
actin
actin-79B

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21985210..21987190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275271.1 → NP_001262200.1  actin 79B, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262200.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02574, Q540X7, Q9VNW5
    UniProtKB/TrEMBL
    C6TP14, M9PFZ6
    Conserved Domains (1) summary
    PTZ00281
    Location:1 → 376
    PTZ00281; actin; Provisional

  2. NM_079486.4 → NP_524210.1  actin 79B, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524210.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02574, Q540X7, Q9VNW5
    UniProtKB/TrEMBL
    C6TP14, M9PFZ6
    Related
    FBpp0078131
    Conserved Domains (1) summary
    PTZ00281
    Location:1 → 376
    PTZ00281; actin; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PFZ6 M9PFZ6
P02574.2 P02574

Gene LinkOut

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