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Zfp992 zinc finger protein 992 [ Mus musculus (house mouse) ]

Gene ID: 433791, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp992provided by MGI
Official Full Name
zinc finger protein 992provided by MGI
Primary source
MGI:MGI:3700963
See related
Ensembl:ENSMUSG00000070605 AllianceGenome:MGI:3700963
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm13251
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 5.1), bladder adult (RPKM 3.6) and 17 other tissues See more
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Genomic context

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See Zfp992 in Genome Data Viewer
Location:
4 E1; 4 78.31 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (146533487..146553897)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (146449030..146469440)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr4:146036310-146036610 Neighboring gene predicted gene, 53231 Neighboring gene predicted gene, 53267 Neighboring gene predicted gene, 53232 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146088873-146089174 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145769232-145769533 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145758419-145758720 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145755844-145756145 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145755071-145755372 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145754273-145754573 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145751280-145751580 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145746825-145747126 Neighboring gene STARR-positive B cell enhancer ABC_E6263 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145737763-145738064 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145736397-145736698 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145733036-145733337 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145715582-145715883 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145714381-145714682 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145711415-145711716 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145707828-145708129 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145704476-145704777 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145703390-145703691 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145702225-145702525 Neighboring gene carnitine deficiency-associated gene expressed in ventricle 3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_12041 Neighboring gene RIKEN cDNA 1700095A21 gene Neighboring gene zinc finger protein 981 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145660367-145660668

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC433791
Names
novel KRAB box containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085522.2 → NP_001078991.1  uncharacterized protein LOC433791

    Status: VALIDATED

    Source sequence(s)
    AL627077, AV583921, BX936357, CJ326493
    Consensus CDS
    CCDS57310.1
    UniProtKB/TrEMBL
    B1ASD8
    Related
    ENSMUSP00000101359.3, ENSMUST00000105733.3
    Conserved Domains (5) summary
    smart00349
    Location:13 → 55
    KRAB; krueppel associated box
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:506 → 530
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    146533487..146553897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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