ada.S adenosine deaminase S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ada.S
Official Full Name: adenosine deaminase S homeolog
Primary source: Xenbase:XB-GENE-950506
Locus tag: XELAEV_18046133mg
See related: EnsemblRapid:ENSXLAG00005036601
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ada; xada
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Genomic context

Location:: chromosome: 9_10S

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10S	NC_054388.1 (7871283..7990628, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10S	NC_030741.1 (7746380..7761406, complement)

Chromosome 9_10S - NC_054388.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables 2'-deoxyadenosine deaminase activity	IEA Inferred from Electronic Annotation more info
enables adenosine deaminase activity	IEA Inferred from Electronic Annotation more info
enables adenosine deaminase activity	ISS Inferred from Sequence or Structural Similarity more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within T cell activation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within adenosine catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within adenosine catabolic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within hypoxanthine salvage	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within inosine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within inosine biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within negative regulation of adenosine receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nucleotide metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within purine ribonucleoside monophosphate biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in anchoring junction	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle lumen	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: adenosine deaminase

Names: adenosine aminohydrolase

NP_001085740.1

EC 3.5.4.4

XP_041433683.1

EC 3.5.4.4

XP_041433684.1

EC 3.5.4.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001092271.1 → NP_001085740.1 adenosine deaminase

See identical proteins and their annotated locations for NP_001085740.1

Status: PROVISIONAL

Source sequence(s)

BC073271

UniProtKB/Swiss-Prot

Q6GP70

UniProtKB/TrEMBL

A0A974BSM4

Related

ENSXLAP00005109559.1, ENSXLAT00005111761.1

Conserved Domains (1) summary

cd01320
Location:7 → 346

ADA; Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

7871283..7990628 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041577749.1 → XP_041433683.1 adenosine deaminase isoform X1

UniProtKB/TrEMBL

A0A8J1LVZ9, A0A974BSM4

Conserved Domains (1) summary

cl00281
Location:7 → 279

metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...
XM_041577750.1 → XP_041433684.1 adenosine deaminase isoform X1

UniProtKB/TrEMBL

A0A8J1LVZ9, A0A974BSM4

Conserved Domains (1) summary

cl00281
Location:7 → 279

metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...