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FKBP4 FKBP prolyl isomerase 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 451748, updated on 29-Mar-2024

Summary

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Official Symbol
FKBP4provided by VGNC
Official Full Name
FKBP prolyl isomerase 4provided by VGNC
Primary source
VGNC:VGNC:5390
Locus tag
CK820_G0037403
See related
Ensembl:ENSPTRG00000004529
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (9967981..9977270)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (8610841..8622796)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134807445 Neighboring gene large ribosomal subunit protein uL23-like Neighboring gene uncharacterized LOC104001402 Neighboring gene integrin alpha FG-GAP repeat containing 2 Neighboring gene nuclear receptor interacting protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein folding chaperone IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peptidyl-prolyl cis-trans isomerase FKBP4
Names
FK506 binding protein 4, 59kDa
XP_009422901.1
XP_063642306.1
XP_508927.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    9967981..9977270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_508927.7 → XP_508927.4  peptidyl-prolyl cis-trans isomerase FKBP4 isoform X1

    UniProtKB/TrEMBL
    A0A2J8KMA7, A0A2J8KMA9, A0A6D2W912, H2Q574, K7B4Z1
    Related
    ENSPTRP00000007751.4
    Conserved Domains (4) summary
    TIGR03516
    Location:155 → 254
    ppisom_GldI; peptidyl-prolyl isomerase, gliding motility-associated
    TIGR02917
    Location:250 → 395
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:274 → 301
    TPR; TPR repeat [structural motif]
    pfam00254
    Location:43 → 134
    FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase

  2. XM_063786236.1 → XP_063642306.1  peptidyl-prolyl cis-trans isomerase FKBP4 isoform X3

  3. XM_009424626.4 → XP_009422901.1  peptidyl-prolyl cis-trans isomerase FKBP4 isoform X2

    UniProtKB/TrEMBL
    A0A2J8KMA9
    Conserved Domains (6) summary
    TIGR03516
    Location:110 → 209
    ppisom_GldI; peptidyl-prolyl isomerase, gliding motility-associated
    sd00006
    Location:229 → 256
    TPR; TPR repeat [structural motif]
    pfam00254
    Location:2 → 89
    FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase
    pfam00515
    Location:276 → 307
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:309 → 341
    TPR_2; Tetratricopeptide repeat
    pfam13414
    Location:277 → 339
    TPR_11; TPR repeat
Nucleotide Protein
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