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PIAS1 protein inhibitor of activated STAT 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 467715, updated on 3-Apr-2024

Summary

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Official Symbol
PIAS1provided by VGNC
Official Full Name
protein inhibitor of activated STAT 1provided by VGNC
Primary source
VGNC:VGNC:13418
Locus tag
CK820_G0008218
See related
Ensembl:ENSPTRG00000007210
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 16 NC_072414.2 (59869067..60180410)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 15 NC_072413.1 (60024258..60158727)

Chromosome 16 - NC_072414.2Genomic Context describing neighboring genes Neighboring gene SKI family transcriptional corepressor 1 Neighboring gene uncharacterized LOC134808551 Neighboring gene U6 spliceosomal RNA Neighboring gene small ribosomal subunit protein uS8-like Neighboring gene uncharacterized LOC134808550 Neighboring gene calmodulin like 4 Neighboring gene uncharacterized LOC107968650 Neighboring gene CLN6 transmembrane ER protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SUMO ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein sumoylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 SUMO-protein ligase PIAS1
XP_054523715.1
XP_063651285.1
XP_063651286.1
XP_063651287.1
XP_063651288.1
XP_523109.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    59869067..60180410
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063795218.1 → XP_063651288.1  E3 SUMO-protein ligase PIAS1 isoform X4

  2. XM_523109.8 → XP_523109.3  E3 SUMO-protein ligase PIAS1 isoform X5

    See identical proteins and their annotated locations for XP_523109.3

    UniProtKB/TrEMBL
    A0A2J8NQZ5, A0A6D2Y6A5, H2Q9P3, H2RH26
    Related
    ENSPTRP00000012341.6
    Conserved Domains (3) summary
    smart00513
    Location:11 → 45
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:332 → 379
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:137 → 285
    PINIT; PINIT domain

  3. XM_063795216.1 → XP_063651286.1  E3 SUMO-protein ligase PIAS1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3SSB8, A0A2J8NQZ7, A0A6D2W8X4

  4. XM_063795217.1 → XP_063651287.1  E3 SUMO-protein ligase PIAS1 isoform X3

  5. XM_063795215.1 → XP_063651285.1  E3 SUMO-protein ligase PIAS1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3SSB8, A0A2J8NQZ7, A0A6D2W8X4

  6. XM_054667740.2 → XP_054523715.1  E3 SUMO-protein ligase PIAS1 isoform X2

Nucleotide Protein
Heading Accession and Version

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