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OGDH oxoglutarate dehydrogenase [ Canis lupus familiaris (dog) ]

Gene ID: 475499, updated on 5-Mar-2024

Summary

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Official Symbol
OGDHprovided by VGNC
Official Full Name
oxoglutarate dehydrogenaseprovided by VGNC
Primary source
VGNC:VGNC:106422
See related
Ensembl:ENSCAFG00845012087
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 16 NC_051820.1 (14428589..14497803, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 16 NC_006598.4 (2363764..2432958)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 16 NC_049237.1 (14040718..14109906, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 16 NC_049757.1 (14059830..14129291, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) Unplaced Scaffold NW_023332296.1 (448077..517261, complement)

Chromosome 16 - NC_051820.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106558496 Neighboring gene uncharacterized LOC119875707 Neighboring gene zinc finger MIZ-type containing 2 Neighboring gene transmembrane p24 trafficking protein 4 Neighboring gene DEAD-box helicase 56

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of oxoglutarate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
2-oxoglutarate dehydrogenase, mitochondrial
XP_038308181.1
XP_038308182.1
XP_038308184.1
XP_038308185.1
XP_038381118.1
XP_038381119.1
XP_038381120.1
XP_038381121.1
XP_038415480.1
XP_038415481.1
XP_038415482.1
XP_038415483.1
XP_038479442.1
XP_038479443.1
XP_038479444.1
XP_038479445.1
XP_038545214.1
XP_038545215.1
XP_038545216.1
XP_038545217.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051820.1 Reference ROS_Cfam_1.0

    Range
    14428589..14497803 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038689287.1 → XP_038545215.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0L890, A0A8C0MJJ2, A0A8P0S943, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1015
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  2. XM_038689289.1 → XP_038545217.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8C0TID3, A0A8I3NKB5, A0A8P0TE49
    Related
    ENSCAFP00845016996.1, ENSCAFT00845021625.1
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1030
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  3. XM_038689288.1 → XP_038545216.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C0TFD2, A0A8P0TE37, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1011
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  4. XM_038689286.1 → XP_038545214.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0MD79, A0A8I3NWZ0, A0A8P0TE49
    Related
    ENSCAFP00845017088.1, ENSCAFT00845021731.1
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1026
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

Alternate UMICH_Zoey_3.1

Genomic

  1. NW_023332296.1 Alternate UMICH_Zoey_3.1

    Range
    448077..517261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038525191.1 → XP_038381119.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X2

    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1015
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  2. XM_038525193.1 → XP_038381121.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X4

    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1030
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  3. XM_038525192.1 → XP_038381120.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X3

    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1011
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  4. XM_038525190.1 → XP_038381118.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1026
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049757.1 Alternate UNSW_CanFamBas_1.0

    Range
    14059830..14129291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038623515.1 → XP_038479443.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X2

    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1015
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  2. XM_038623517.1 → XP_038479445.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X4

    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1030
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  3. XM_038623516.1 → XP_038479444.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X3

    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1011
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  4. XM_038623514.1 → XP_038479442.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1026
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049237.1 Alternate UU_Cfam_GSD_1.0

    Range
    14040718..14109906 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038559553.1 → XP_038415481.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0L890, A0A8C0MJJ2, A0A8P0S943, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1015
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  2. XM_038559555.1 → XP_038415483.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8C0TID3, A0A8I3NKB5, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1030
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  3. XM_038559554.1 → XP_038415482.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C0TFD2, A0A8P0TE37, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1011
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  4. XM_038559552.1 → XP_038415480.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0MD79, A0A8I3NWZ0, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1026
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006598.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    2363764..2432958
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038452253.1 → XP_038308181.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0MD79, A0A8I3NWZ0, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1026
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  2. XM_038452256.1 → XP_038308184.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C0TFD2, A0A8P0TE37, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1011
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  3. XM_038452257.1 → XP_038308185.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8C0TID3, A0A8I3NKB5, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1030
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  4. XM_038452254.1 → XP_038308182.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0L890, A0A8C0MJJ2, A0A8P0S943, A0A8P0TE49
    Conserved Domains (1) summary
    PRK09404
    Location:49 → 1015
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
Nucleotide Protein
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