U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RIPK2 receptor interacting serine/threonine kinase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 477936, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
RIPK2provided by VGNC
Official Full Name
receptor interacting serine/threonine kinase 2provided by VGNC
Primary source
VGNC:VGNC:45595
See related
Ensembl:ENSCAFG00845018948
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 29
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 29 NC_051833.1 (35480726..35509728)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 29 NC_006611.4 (35435813..35464812)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 29 NC_049250.1 (35926135..35955236)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 29 NC_049289.1 (35472061..35501046)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 29 NC_049770.1 (35492803..35521758)

Chromosome 29 - NC_051833.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093093 Neighboring gene uncharacterized LOC111093098 Neighboring gene developmental pluripotency-associated protein 4-like Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC111093094 Neighboring gene uncharacterized LOC111093099

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables JUN kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
receptor-interacting serine/threonine-protein kinase 2
XP_005638158.2
XP_005638159.1
XP_038297488.1
XP_038297489.1
XP_038372058.1
XP_038372059.1
XP_038435630.1
XP_038435631.1
XP_038499869.1
XP_038499870.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051833.1 Reference ROS_Cfam_1.0

    Range
    35480726..35509728
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441560.1 → XP_038297488.1  receptor-interacting serine/threonine-protein kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PH03, A0A8C0T3F0, A0A8I3PFI5, A0A8I3PFP0
    Related
    ENSCAFP00845026197.1, ENSCAFT00845033465.1
    Conserved Domains (2) summary
    cd08786
    Location:436 → 522
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cd14026
    Location:20 → 303
    STKc_RIP2; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 2

  2. XM_038441561.1 → XP_038297489.1  receptor-interacting serine/threonine-protein kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KGT6, A0A8C0PQC0, A0A8C0T3F0, A0A8I3P3I2, A0A8I3PFP0
    Related
    ENSCAFP00845026352.1, ENSCAFT00845033658.1
    Conserved Domains (2) summary
    cd08786
    Location:393 → 479
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cl21453
    Location:16 → 260
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049289.1 Alternate UMICH_Zoey_3.1

    Range
    35472061..35501046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516130.1 → XP_038372058.1  receptor-interacting serine/threonine-protein kinase 2 isoform X1

    Conserved Domains (2) summary
    cd08786
    Location:436 → 522
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cd14026
    Location:20 → 303
    STKc_RIP2; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 2

  2. XM_038516131.1 → XP_038372059.1  receptor-interacting serine/threonine-protein kinase 2 isoform X2

    Conserved Domains (2) summary
    cd08786
    Location:393 → 479
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cl21453
    Location:16 → 260
    PKc_like; Protein Kinases, catalytic domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049770.1 Alternate UNSW_CanFamBas_1.0

    Range
    35492803..35521758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038643941.1 → XP_038499869.1  receptor-interacting serine/threonine-protein kinase 2 isoform X1

    Conserved Domains (2) summary
    cd08786
    Location:436 → 522
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cd14026
    Location:20 → 303
    STKc_RIP2; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 2

  2. XM_038643942.1 → XP_038499870.1  receptor-interacting serine/threonine-protein kinase 2 isoform X2

    Conserved Domains (2) summary
    cd08786
    Location:393 → 479
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cl21453
    Location:16 → 260
    PKc_like; Protein Kinases, catalytic domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049250.1 Alternate UU_Cfam_GSD_1.0

    Range
    35926135..35955236
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579702.1 → XP_038435630.1  receptor-interacting serine/threonine-protein kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PH03, A0A8C0T3F0, A0A8I3PFI5, A0A8I3PFP0
    Conserved Domains (2) summary
    cd08786
    Location:436 → 522
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cd14026
    Location:20 → 303
    STKc_RIP2; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 2

  2. XM_038579703.1 → XP_038435631.1  receptor-interacting serine/threonine-protein kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KGT6, A0A8C0PQC0, A0A8C0T3F0, A0A8I3P3I2, A0A8I3PFP0
    Conserved Domains (2) summary
    cd08786
    Location:393 → 479
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cl21453
    Location:16 → 260
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006611.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    35435813..35464812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005638101.4 → XP_005638158.2  receptor-interacting serine/threonine-protein kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PH03, A0A8C0T3F0, A0A8I3PFI5, A0A8I3PFP0
    Conserved Domains (2) summary
    cd08786
    Location:436 → 522
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cd14026
    Location:20 → 303
    STKc_RIP2; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 2

  2. XM_005638102.4 → XP_005638159.1  receptor-interacting serine/threonine-protein kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KGT6, A0A8C0PQC0, A0A8C0T3F0, A0A8I3P3I2, A0A8I3PFP0
    Conserved Domains (2) summary
    cd08786
    Location:393 → 479
    CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2
    cl21453
    Location:16 → 260
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous