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nog noggin [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 493191, updated on 4-Jan-2025

Summary

Official Symbol
nogprovided by Xenbase
Official Full Name
nogginprovided by Xenbase
Primary source
Xenbase:XB-GENE-487724
See related
Ensembl:ENSXETG00000043161 AllianceGenome:Xenbase:XB-GENE-487724
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
nog1; nog-A; Noggin1; noggin-1
Summary
Predicted to be involved in dorsal/ventral pattern formation; negative regulation of BMP signaling pathway; and osteoblast differentiation. Predicted to act upstream of or within cartilage development; cell differentiation; and negative regulation of cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in musculoskeletal system; nervous system; pharyngeal arch; and primary germ layer. Human ortholog(s) of this gene implicated in Huntington's disease; bone disease (multiple); cleft lip; and hyperopia. Orthologous to human NOG (noggin). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See nog in Genome Data Viewer
Location:
chromosome: 10
Exon count:
1
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (25898656..25899324)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 10 NC_030686.1 (18049260..18049928)

Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 100 Neighboring gene ankyrin repeat and fibronectin type III domain containing 1 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC105945278 Neighboring gene chromosome 10 C17orf67 homolog Neighboring gene uncharacterized LOC116407950

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Component Evidence Code Pubs
located_in extracellular region  
is_active_in extracellular space  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001171898.1NP_001165369.1  noggin

    See identical proteins and their annotated locations for NP_001165369.1

    Status: PROVISIONAL

    Source sequence(s)
    AY672091
    UniProtKB/TrEMBL
    F6RNY4, Q6BA00
    Related
    ENSXETP00000117159.1, ENSXETT00000120514.1
    Conserved Domains (1) summary
    pfam05806
    Location:11222
    Noggin

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    25898656..25899324
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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