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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001012408.1 → NP_001012408.1 dystrophin
See identical proteins and their annotated locations for NP_001012408.1
Status: PROVISIONAL
- Source sequence(s)
-
AJ865385
- UniProtKB/Swiss-Prot
-
Q5GN48
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (10) summary
-
- COG1340
Location:1700 → 1970
- COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
- cd00014
Location:12 → 115
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:340 → 554
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3048 → 3077
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3300 → 3348
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2923 → 3029
- Spectrin; Spectrin repeat
- pfam09068
Location:3078 → 3196
- EF-hand_2; EF hand
- pfam09069
Location:3200 → 3291
- EF-hand_3; EF-hand
- pfam16769
Location:3477 → 3660
- MCM3AP_GANP; MCM3AP domain of GANP
- cl02488
Location:1492 → 1672
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference Sscrofa11.1 Primary Assembly
Genomic
-
NC_010461.5 Reference Sscrofa11.1 Primary Assembly
- Range
-
27028223..29650728 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_021079543.1 → XP_020935202.1 dystrophin isoform X1
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:27 → 249
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:362 → 576
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3070 → 3099
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3322 → 3370
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2945 → 3051
- Spectrin; Spectrin repeat
- pfam16769
Location:3499 → 3692
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3136 → 3297
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:578 → 845
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1134 → 1954
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079551.1 → XP_020935210.1 dystrophin isoform X9
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:27 → 249
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:362 → 576
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3013 → 3042
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3265 → 3313
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2888 → 2994
- Spectrin; Spectrin repeat
- pfam16769
Location:3442 → 3635
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3079 → 3240
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:578 → 845
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1134 → 2015
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079550.1 → XP_020935209.1 dystrophin isoform X8
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:27 → 249
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:362 → 576
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3070 → 3099
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3322 → 3370
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2945 → 3051
- Spectrin; Spectrin repeat
- pfam16769
Location:3464 → 3657
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3136 → 3297
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:578 → 845
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1134 → 1954
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079544.1 → XP_020935203.1 dystrophin isoform X2
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:27 → 249
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:362 → 576
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3070 → 3099
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3322 → 3370
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2945 → 3051
- Spectrin; Spectrin repeat
- pfam16769
Location:3486 → 3679
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3136 → 3297
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:578 → 845
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1134 → 1954
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079554.1 → XP_020935213.1 dystrophin isoform X11
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:27 → 249
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:362 → 576
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3009 → 3038
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3261 → 3309
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2884 → 2990
- Spectrin; Spectrin repeat
- pfam16769
Location:3438 → 3631
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3075 → 3236
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:578 → 845
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1134 → 2011
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079549.1 → XP_020935208.1 dystrophin isoform X7
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (8) summary
-
- COG5069
Location:27 → 249
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:362 → 576
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3070 → 3099
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3322 → 3370
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2945 → 3051
- Spectrin; Spectrin repeat
- cd16246
Location:3136 → 3297
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:578 → 845
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1134 → 1954
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079546.1 → XP_020935205.1 dystrophin isoform X4
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (8) summary
-
- COG5069
Location:27 → 249
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:362 → 576
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3070 → 3099
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3322 → 3370
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2945 → 3051
- Spectrin; Spectrin repeat
- cd16246
Location:3136 → 3297
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:578 → 845
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1134 → 1954
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079555.1 → XP_020935214.1 dystrophin isoform X12
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:2 → 224
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:293 → 507
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3001 → 3030
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3253 → 3301
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2876 → 2982
- Spectrin; Spectrin repeat
- pfam16769
Location:3430 → 3623
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3067 → 3228
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:509 → 776
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1065 → 1885
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079556.1 → XP_020935215.1 dystrophin isoform X13
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:2 → 224
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:337 → 551
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:2988 → 3017
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3240 → 3288
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2863 → 2969
- Spectrin; Spectrin repeat
- pfam16769
Location:3417 → 3610
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3054 → 3215
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:553 → 820
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1109 → 1990
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079548.1 → XP_020935207.1 dystrophin isoform X6
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:2 → 224
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:337 → 551
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3045 → 3074
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3297 → 3345
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2920 → 3026
- Spectrin; Spectrin repeat
- pfam16769
Location:3474 → 3667
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3111 → 3272
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:553 → 820
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1109 → 1929
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079553.1 → XP_020935212.1 dystrophin isoform X10
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:12 → 232
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:301 → 515
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3009 → 3038
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3261 → 3309
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2884 → 2990
- Spectrin; Spectrin repeat
- pfam16769
Location:3438 → 3631
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3075 → 3236
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:517 → 784
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1073 → 1893
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079545.1 → XP_020935204.1 dystrophin isoform X3
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:12 → 232
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:345 → 559
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3053 → 3082
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3305 → 3353
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2928 → 3034
- Spectrin; Spectrin repeat
- pfam16769
Location:3482 → 3675
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3119 → 3280
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:561 → 828
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1117 → 1937
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079547.1 → XP_020935206.1 dystrophin isoform X5
- UniProtKB/TrEMBL
-
A0A480Z486
- Conserved Domains (9) summary
-
- COG5069
Location:8 → 228
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00176
Location:341 → 555
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:3049 → 3078
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:3301 → 3349
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2924 → 3030
- Spectrin; Spectrin repeat
- pfam16769
Location:3478 → 3671
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:3115 → 3276
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:557 → 824
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:1113 → 1933
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079557.1 → XP_020935216.1 dystrophin isoform X14
- Conserved Domains (8) summary
-
- cd00176
Location:1315 → 1528
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:2262 → 2291
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:2514 → 2562
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2137 → 2243
- Spectrin; Spectrin repeat
- pfam16769
Location:2691 → 2884
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:2328 → 2489
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:7 → 143
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:326 → 1146
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079558.1 → XP_020935217.1 dystrophin isoform X14
- Conserved Domains (8) summary
-
- cd00176
Location:1315 → 1528
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:2262 → 2291
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:2514 → 2562
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:2137 → 2243
- Spectrin; Spectrin repeat
- pfam16769
Location:2691 → 2884
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:2328 → 2489
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl02488
Location:7 → 143
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cl25732
Location:326 → 1146
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079559.1 → XP_020935218.1 dystrophin isoform X15
- UniProtKB/TrEMBL
- A0A5G2QY27, A0A8D1M2E2, A0A8D1TC61
- Related
- ENSSSCP00000066851.1, ENSSSCT00000087025.2
- Conserved Domains (6) summary
-
- cd00176
Location:230 → 473
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:599 → 628
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:851 → 899
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:474 → 580
- Spectrin; Spectrin repeat
- pfam16769
Location:1028 → 1221
- MCM3AP_GANP; MCM3AP domain of GANP
- cd16246
Location:665 → 826
- EFh_DMD; EF-hand-like motif found in dystrophin
-
XM_021079560.1 → XP_020935219.1 dystrophin isoform X16
- UniProtKB/TrEMBL
-
A0A8D2BJZ1
- Related
- ENSSSCP00000012992.6, ENSSSCT00000013350.6
- Conserved Domains (6) summary
-
- cd00176
Location:24 → 218
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd00201
Location:344 → 373
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd02334
Location:596 → 644
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- pfam00435
Location:219 → 325
- Spectrin; Spectrin repeat
- cd16246
Location:410 → 571
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl25732
Location:720 → 890
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079561.1 → XP_020935220.1 dystrophin isoform X17
- UniProtKB/TrEMBL
- A0A8D0S4D0, A0A8D1VFH6
- Conserved Domains (3) summary
-
- cd02334
Location:243 → 291
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- cd16246
Location:57 → 218
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl25732
Location:367 → 537
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079562.1 → XP_020935221.1 dystrophin isoform X18
- UniProtKB/TrEMBL
- A0A8D0S4D0, A0A8D1S885
- Conserved Domains (3) summary
-
- cd02334
Location:243 → 291
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- cd16246
Location:57 → 218
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl25732
Location:354 → 524
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079565.1 → XP_020935224.1 dystrophin isoform X20
- UniProtKB/TrEMBL
-
A0A8D0S4D0
- Conserved Domains (3) summary
-
- cd02334
Location:243 → 291
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- cd16246
Location:57 → 218
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl25732
Location:354 → 524
- SMC_N; RecF/RecN/SMC N terminal domain
-
XM_021079564.1 → XP_020935223.1 dystrophin isoform X19
- UniProtKB/TrEMBL
- A0A8D0S4D0, A0A8D0VCI5
- Conserved Domains (3) summary
-
- cd02334
Location:243 → 291
- ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
- cd16246
Location:57 → 218
- EFh_DMD; EF-hand-like motif found in dystrophin
- cl25732
Location:367 → 537
- SMC_N; RecF/RecN/SMC N terminal domain