Nrcam neuronal cell adhesion molecule [ Rattus norvegicus (Norway rat) ]

Gene ID: 497815, updated on 2-May-2024

Summary

Official Symbol: Nrcamprovided by RGD
Official Full Name: neuronal cell adhesion moleculeprovided by RGD
Primary source: RGD:3209
See related: Ensembl:ENSRNOG00000004067 AllianceGenome:RGD:3209
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ankyrin binding activity and protein binding activity involved in heterotypic cell-cell adhesion. Predicted to be involved in several processes, including angiogenesis; homophilic cell adhesion via plasma membrane adhesion molecules; and neuron development. Predicted to act upstream of or within several processes, including neuronal action potential propagation; regulation of neuron projection development; and retinal ganglion cell axon guidance. Located in axon initial segment and node of Ranvier. Orthologous to human NRCAM (neuronal cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 599.3) and Adrenal (RPKM 228.7) See more
Orthologs: human mouse all
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Genomic context

Location:: 6q21

Exon count:: 36

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (67129723..67425510)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (61402813..61698536)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (64297843..64867408)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

We identified a key alternative splicing event of Nrcam (Nrcam-S) as an important candidate in promoting axon regeneration
Title: Alternative RNA splicing associated with axon regeneration after rat peripheral nerve injury.
This is the first interaction reported for NrCAM, and its association with SAP102 suggests that it is part of a larger complex which can interact with many different signalling pathways.
Title: Synapse associated protein 102 is a novel binding partner to the cytoplasmic terminus of neurone-glial related cell adhesion molecule.
Results suggest that anchoring of NrCAM with retrograde actin flow can be triggered by adhesive contacts via cooperative processes.
Title: NrCAM coupling to the cytoskeleton depends on multiple protein domains and partitioning into lipid rafts.
Gliomedin, a Schwann cell ligand for both neurofascin and Nrcam that is localized to the nodal microvilli from the onset of myelination.
Title: Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH140409 (e-PCR)
- UniSTS:222484

AW535153 (e-PCR)
- UniSTS:247191

RH94713 (e-PCR)
- UniSTS:119960

RH141931 (e-PCR)
- UniSTS:223922

D6Rat24 (e-PCR)
- UniSTS:118963

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ankyrin binding	ISO Inferred from Sequence Orthology more info
enables ankyrin binding	ISS Inferred from Sequence or Structural Similarity more info
enables ankyrin binding	TAS Traceable Author Statement more info	PubMed
enables cell-cell adhesion mediator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding involved in heterotypic cell-cell adhesion	IEA Inferred from Electronic Annotation more info
enables protein binding involved in heterotypic cell-cell adhesion	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in angiogenesis	ISO Inferred from Sequence Orthology more info
involved_in axon guidance	IBA Inferred from Biological aspect of Ancestor more info
involved_in axon guidance	ISO Inferred from Sequence Orthology more info
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in cell adhesion	TAS Traceable Author Statement more info	PubMed
involved_in cell-cell adhesion	ISO Inferred from Sequence Orthology more info
involved_in central nervous system development	IEA Inferred from Electronic Annotation more info
involved_in central nervous system development	ISO Inferred from Sequence Orthology more info
involved_in central nervous system development	ISS Inferred from Sequence or Structural Similarity more info
involved_in clustering of voltage-gated sodium channels	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within clustering of voltage-gated sodium channels	ISO Inferred from Sequence Orthology more info
involved_in clustering of voltage-gated sodium channels	ISO Inferred from Sequence Orthology more info
involved_in clustering of voltage-gated sodium channels	ISS Inferred from Sequence or Structural Similarity more info
involved_in dendrite self-avoidance	IBA Inferred from Biological aspect of Ancestor more info
involved_in heterotypic cell-cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in homophilic cell adhesion via plasma membrane adhesion molecules	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuronal action potential propagation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neuronal action potential propagation	ISO Inferred from Sequence Orthology more info
involved_in protein localization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein localization	ISO Inferred from Sequence Orthology more info
involved_in regulation of neuron projection development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of neuron projection development	ISO Inferred from Sequence Orthology more info
involved_in regulation of postsynapse organization	IEA Inferred from Electronic Annotation more info
involved_in regulation of postsynapse organization	ISO Inferred from Sequence Orthology more info
involved_in retinal ganglion cell axon guidance	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within retinal ganglion cell axon guidance	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in axon	IBA Inferred from Biological aspect of Ancestor more info
located_in axon	IDA Inferred from Direct Assay more info	PubMed
located_in axon	IEA Inferred from Electronic Annotation more info
located_in axon	ISO Inferred from Sequence Orthology more info
located_in axon initial segment	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in glutamatergic synapse	IEA Inferred from Electronic Annotation more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in neuron projection	IEA Inferred from Electronic Annotation more info
located_in node of Ranvier	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	TAS Traceable Author Statement more info
located_in postsynaptic density membrane	IEA Inferred from Electronic Annotation more info
is_active_in postsynaptic density membrane	ISO Inferred from Sequence Orthology more info
is_active_in postsynaptic membrane	ISO Inferred from Sequence Orthology more info
located_in synapse	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: neuronal cell adhesion molecule

Names: ankyrin-binding cell adhesion molecule NrCAM; neuron-glia-CAM-related cell adhesion molecule; neuronal surface protein Bravo; ng-CAM-related; ngCAM-related cell adhesion molecule; nr-CAM; rBravo

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_013150.3 → NP_037282.2 neuronal cell adhesion molecule precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000006

UniProtKB/TrEMBL

A0A0G2K498, D3ZXM9, Q6PW34

Related

ENSRNOP00000072959.2, ENSRNOT00000083088.3

Conserved Domains (6) summary

smart00408
Location:285 → 347

IGc2; Immunoglobulin C-2 Type

smart00060
Location:1079 → 1143

FN3; Fibronectin type 3 domain

smart00409
Location:552 → 633

IG; Immunoglobulin

smart00410
Location:367 → 449

IG_like; Immunoglobulin like

cd00063
Location:647 → 737

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cd00096
Location:288 → 292

Ig; Ig strand B [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086024.1 Reference GRCr8

Range

67129723..67425510

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063262283.1 → XP_063118353.1 neuronal cell adhesion molecule isoform X42
XM_063262272.1 → XP_063118342.1 neuronal cell adhesion molecule isoform X31
XM_063262274.1 → XP_063118344.1 neuronal cell adhesion molecule isoform X33
XM_063262275.1 → XP_063118345.1 neuronal cell adhesion molecule isoform X35
XM_063262280.1 → XP_063118350.1 neuronal cell adhesion molecule isoform X40
XM_039112675.2 → XP_038968603.1 neuronal cell adhesion molecule isoform X1

UniProtKB/TrEMBL

D3ZXM9, Q6PW34

Conserved Domains (6) summary

cd00063
Location:651 → 741

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:957 → 1041

fn3; Fibronectin type III domain

pfam13882
Location:1198 → 1283

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:382 → 386

Ig; Ig strand B [structural motif]

cd05874
Location:50 → 144

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:366 → 454

Ig; Immunoglobulin domain
XM_063262268.1 → XP_063118338.1 neuronal cell adhesion molecule isoform X12
XM_017594282.3 → XP_017449771.1 neuronal cell adhesion molecule isoform X15

UniProtKB/Swiss-Prot

P97686
XM_017594288.3 → XP_017449777.1 neuronal cell adhesion molecule isoform X19

UniProtKB/TrEMBL

D4A8C2, Q6PW38
XM_017594273.3 → XP_017449762.1 neuronal cell adhesion molecule isoform X3

UniProtKB/TrEMBL

D3ZXM9, Q6PW34
XM_017594283.3 → XP_017449772.1 neuronal cell adhesion molecule isoform X16

UniProtKB/Swiss-Prot

P97686
XM_063262264.1 → XP_063118334.1 neuronal cell adhesion molecule isoform X5
XM_017594289.3 → XP_017449778.1 neuronal cell adhesion molecule isoform X20

UniProtKB/TrEMBL

Q6PW35
XM_063262269.1 → XP_063118339.1 neuronal cell adhesion molecule isoform X24
XM_039112699.2 → XP_038968627.1 neuronal cell adhesion molecule isoform X26

UniProtKB/TrEMBL

Q6PW35

Conserved Domains (6) summary

cd00063
Location:641 → 731

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:947 → 1031

fn3; Fibronectin type III domain

pfam13882
Location:1080 → 1165

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:382 → 386

Ig; Ig strand B [structural motif]

cd05874
Location:50 → 144

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:366 → 454

Ig; Immunoglobulin domain
XM_063262273.1 → XP_063118343.1 neuronal cell adhesion molecule isoform X32
XM_039112684.2 → XP_038968612.1 neuronal cell adhesion molecule isoform X7

UniProtKB/TrEMBL

D3ZXM9, Q6PW34

Conserved Domains (6) summary

cd00063
Location:632 → 722

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:938 → 1022

fn3; Fibronectin type III domain

pfam13882
Location:1176 → 1261

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:363 → 367

Ig; Ig strand B [structural motif]

cd05874
Location:50 → 144

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:347 → 435

Ig; Immunoglobulin domain
XM_039112695.2 → XP_038968623.1 neuronal cell adhesion molecule isoform X23

UniProtKB/Swiss-Prot

P97686

Conserved Domains (6) summary

cd00063
Location:632 → 722

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:938 → 1022

fn3; Fibronectin type III domain

pfam13882
Location:1083 → 1168

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:363 → 367

Ig; Ig strand B [structural motif]

cd05874
Location:50 → 144

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:347 → 435

Ig; Immunoglobulin domain
XM_063262266.1 → XP_063118336.1 neuronal cell adhesion molecule isoform X10
XM_063262276.1 → XP_063118346.1 neuronal cell adhesion molecule isoform X37
XM_063262277.1 → XP_063118347.1 neuronal cell adhesion molecule isoform X38
XM_039112676.2 → XP_038968604.1 neuronal cell adhesion molecule isoform X4

UniProtKB/TrEMBL

D3ZXM9, Q6PW34

Conserved Domains (6) summary

cd00063
Location:647 → 737

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:953 → 1037

fn3; Fibronectin type III domain

pfam13882
Location:1194 → 1279

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:378 → 382

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:362 → 450

Ig; Immunoglobulin domain
XM_017594284.3 → XP_017449773.1 neuronal cell adhesion molecule isoform X17

UniProtKB/Swiss-Prot

P97686

UniProtKB/TrEMBL

A0A8J8YHB8

Related

ENSRNOP00000056494.5
XM_017594290.3 → XP_017449779.1 neuronal cell adhesion molecule isoform X21

UniProtKB/TrEMBL

A0A1W5DU98, D4A8C2, Q6PW38

Related

ENSRNOP00000044341.6
XM_017594272.3 → XP_017449761.1 neuronal cell adhesion molecule isoform X2

UniProtKB/TrEMBL

A0A0G2JW27, D3ZXM9, Q6PW34

Related

ENSRNOP00000069715.2
XM_017594285.3 → XP_017449774.1 neuronal cell adhesion molecule isoform X18

UniProtKB/Swiss-Prot

P97686

Related

ENSRNOP00000072479.2
XM_063262265.1 → XP_063118335.1 neuronal cell adhesion molecule isoform X6
XM_017594291.3 → XP_017449780.1 neuronal cell adhesion molecule isoform X22

UniProtKB/TrEMBL

Q6PW35
XM_039112701.2 → XP_038968629.1 neuronal cell adhesion molecule isoform X28

UniProtKB/TrEMBL

D4A8C2, Q6PW38

Conserved Domains (6) summary

cd00063
Location:637 → 727

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:943 → 1027

fn3; Fibronectin type III domain

pfam13882
Location:1079 → 1164

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:378 → 382

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:362 → 450

Ig; Immunoglobulin domain
XM_039112702.2 → XP_038968630.1 neuronal cell adhesion molecule isoform X30

UniProtKB/TrEMBL

Q6PW35

Conserved Domains (6) summary

cd00063
Location:637 → 727

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:943 → 1027

fn3; Fibronectin type III domain

pfam13882
Location:1076 → 1161

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:378 → 382

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:362 → 450

Ig; Immunoglobulin domain
XM_039112685.2 → XP_038968613.1 neuronal cell adhesion molecule isoform X8

UniProtKB/TrEMBL

D3ZXM9, Q6PW34

Conserved Domains (6) summary

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:934 → 1018

fn3; Fibronectin type III domain

pfam13882
Location:1175 → 1260

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:359 → 363

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:343 → 431

Ig; Immunoglobulin domain
XM_039112696.2 → XP_038968624.1 neuronal cell adhesion molecule isoform X25

UniProtKB/Swiss-Prot

P97686

UniProtKB/TrEMBL

A0A8I6ADS1

Related

ENSRNOP00000091467.1

Conserved Domains (6) summary

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:934 → 1018

fn3; Fibronectin type III domain

pfam13882
Location:1082 → 1167

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:359 → 363

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:343 → 431

Ig; Immunoglobulin domain
XM_039112705.2 → XP_038968633.1 neuronal cell adhesion molecule isoform X34

UniProtKB/TrEMBL

D4A8C2, Q6PW38

Conserved Domains (6) summary

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:934 → 1018

fn3; Fibronectin type III domain

pfam13882
Location:1070 → 1155

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:359 → 363

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:343 → 431

Ig; Immunoglobulin domain
XM_039112686.2 → XP_038968614.1 neuronal cell adhesion molecule isoform X9

UniProtKB/TrEMBL

D3ZXM9, Q6PW34

Conserved Domains (6) summary

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:934 → 1018

fn3; Fibronectin type III domain

pfam13882
Location:1172 → 1257

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:359 → 363

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:343 → 431

Ig; Immunoglobulin domain
XM_039112690.2 → XP_038968618.1 neuronal cell adhesion molecule isoform X14

UniProtKB/TrEMBL

D3ZXM9, Q6PW34

Conserved Domains (6) summary

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:934 → 1018

fn3; Fibronectin type III domain

pfam13882
Location:1130 → 1215

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:359 → 363

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:343 → 431

Ig; Immunoglobulin domain
XM_039112700.2 → XP_038968628.1 neuronal cell adhesion molecule isoform X27

UniProtKB/Swiss-Prot

P97686

Conserved Domains (6) summary

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:934 → 1018

fn3; Fibronectin type III domain

pfam13882
Location:1079 → 1164

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:359 → 363

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:343 → 431

Ig; Immunoglobulin domain
XM_063262267.1 → XP_063118337.1 neuronal cell adhesion molecule isoform X11
XM_039112707.2 → XP_038968635.1 neuronal cell adhesion molecule isoform X36

UniProtKB/TrEMBL

Q6PW35

Conserved Domains (6) summary

cd00063
Location:628 → 718

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:934 → 1018

fn3; Fibronectin type III domain

pfam13882
Location:1067 → 1152

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:359 → 363

Ig; Ig strand B [structural motif]

cd05874
Location:46 → 140

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:343 → 431

Ig; Immunoglobulin domain
XM_063262270.1 → XP_063118340.1 neuronal cell adhesion molecule isoform X29
XM_039112689.2 → XP_038968617.1 neuronal cell adhesion molecule isoform X13

UniProtKB/TrEMBL

A0A0G2K3Q5, A6HBE7

Related

ENSRNOP00000072733.2

Conserved Domains (6) summary

cd00063
Location:641 → 731

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:947 → 1031

fn3; Fibronectin type III domain

pfam13882
Location:1143 → 1228

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:372 → 376

Ig; Ig strand B [structural motif]

cd05874
Location:40 → 134

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:356 → 444

Ig; Immunoglobulin domain
XM_063262271.1 → XP_063118341.1 neuronal cell adhesion molecule isoform X31
XM_039112704.2 → XP_038968632.1 neuronal cell adhesion molecule isoform X33

UniProtKB/TrEMBL

A6HBE7, D4A8C2, Q6PW38

Related

ENSRNOP00000076330.2

Conserved Domains (6) summary

cd00063
Location:631 → 721

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:937 → 1021

fn3; Fibronectin type III domain

pfam13882
Location:1073 → 1158

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:372 → 376

Ig; Ig strand B [structural motif]

cd05874
Location:40 → 134

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:356 → 444

Ig; Immunoglobulin domain
XM_063262284.1 → XP_063118354.1 neuronal cell adhesion molecule isoform X43
XM_039112706.2 → XP_038968634.1 neuronal cell adhesion molecule isoform X35

UniProtKB/TrEMBL

Q6PW35

Conserved Domains (6) summary

cd00063
Location:631 → 721

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:937 → 1021

fn3; Fibronectin type III domain

pfam13882
Location:1070 → 1155

Bravo_FIGEY; Bravo-like intracellular region

cd00096
Location:372 → 376

Ig; Ig strand B [structural motif]

cd05874
Location:40 → 134

IgI_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule); member of the I-set of Ig superfamily (IgSF) domains

cl11960
Location:356 → 444

Ig; Immunoglobulin domain
XM_063262278.1 → XP_063118348.1 neuronal cell adhesion molecule isoform X39
XM_063262279.1 → XP_063118349.1 neuronal cell adhesion molecule isoform X40
XM_063262281.1 → XP_063118351.1 neuronal cell adhesion molecule isoform X41
XM_063262282.1 → XP_063118352.1 neuronal cell adhesion molecule isoform X42