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Zfp286a zinc finger protein 286A [ Rattus norvegicus (Norway rat) ]

Gene ID: 497923, updated on 13-Apr-2024

Summary

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Official Symbol
Zfp286aprovided by RGD
Official Full Name
zinc finger protein 286Aprovided by RGD
Primary source
RGD:1561950
See related
Ensembl:ENSRNOG00000003218 AllianceGenome:RGD:1561950
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zfp286; Znf286a; RGD1561950
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF286A (zinc finger protein 286A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 40.1), Brain (RPKM 28.2) and 8 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp286a in Genome Data Viewer
Location:
10q23
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (47949698..47960496, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (47450469..47461267, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (49185906..49196765, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA67 Neighboring gene tripartite motif-containing 16 Neighboring gene F-box and WD repeat domain containing 10 Neighboring gene U4 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 286A
Names
zinc finger protein 286

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191921.1 → NP_001178850.1  zinc finger protein 286A

    See identical proteins and their annotated locations for NP_001178850.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A0G2K5Q4, A6HFC1, D4A514
    Related
    ENSRNOP00000004294.6, ENSRNOT00000004294.7
    Conserved Domains (6) summary
    smart00349
    Location:50 → 94
    KRAB; krueppel associated box
    COG5048
    Location:351 → 506
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:383 → 403
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:353 → 375
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:50 → 85
    KRAB; KRAB box
    pfam13465
    Location:423 → 448
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    47949698..47960496 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086570.2 → XP_038942498.1  zinc finger protein 286A isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:44 → 88
    KRAB; krueppel associated box
    COG5048
    Location:345 → 500
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:377 → 397
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_017597449.3 → XP_017452938.1  zinc finger protein 286A isoform X2

    UniProtKB/TrEMBL
    D4A514
    Conserved Domains (3) summary
    smart00349
    Location:1 → 52
    KRAB; krueppel associated box
    COG5048
    Location:295 → 450
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_039086571.2 → XP_038942499.1  zinc finger protein 286A isoform X2

    Conserved Domains (3) summary
    smart00349
    Location:1 → 52
    KRAB; krueppel associated box
    COG5048
    Location:295 → 450
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_017597450.3 → XP_017452939.1  zinc finger protein 286A isoform X2

    UniProtKB/TrEMBL
    D4A514
    Conserved Domains (3) summary
    smart00349
    Location:1 → 52
    KRAB; krueppel associated box
    COG5048
    Location:295 → 450
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:327 → 347
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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