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Zfp652 zinc finger protein 652 [ Rattus norvegicus (Norway rat) ]

Gene ID: 497984, updated on 5-Mar-2024

Summary

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Official Symbol
Zfp652provided by RGD
Official Full Name
zinc finger protein 652provided by RGD
Primary source
RGD:1566329
See related
Ensembl:ENSRNOG00000017001 AllianceGenome:RGD:1566329
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf652; RGD1566329
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF652 (zinc finger protein 652). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 120.4), Spleen (RPKM 98.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp652 in Genome Data Viewer
Location:
10q26
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (81123326..81203153)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (80626555..80706397)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (83556809..83572014)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene nerve growth factor receptor Neighboring gene prohibitin 1 Neighboring gene uncharacterized LOC120095179 Neighboring gene uncharacterized LOC102547047 Neighboring gene phosphoethanolamine/phosphocholine phosphatase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC156681

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 652

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080207.1 → NP_001073676.1  zinc finger protein 652

    See identical proteins and their annotated locations for NP_001073676.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129097
    UniProtKB/Swiss-Prot
    A1L1J6
    UniProtKB/TrEMBL
    A6HIA9
    Related
    ENSRNOP00000052376.2, ENSRNOT00000022811.7
    Conserved Domains (3) summary
    COG5048
    Location:438 → 487
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:380 → 463
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:386 → 406
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    81123326..81203153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086629.2 → XP_038942557.1  zinc finger protein 652 isoform X1

    UniProtKB/Swiss-Prot
    A1L1J6
    UniProtKB/TrEMBL
    A6HIA9
    Conserved Domains (3) summary
    COG5048
    Location:438 → 487
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:380 → 463
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:386 → 406
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_039086628.2 → XP_038942556.1  zinc finger protein 652 isoform X1

    UniProtKB/Swiss-Prot
    A1L1J6
    UniProtKB/TrEMBL
    A6HIA9
    Conserved Domains (3) summary
    COG5048
    Location:438 → 487
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:380 → 463
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:386 → 406
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_039086627.2 → XP_038942555.1  zinc finger protein 652 isoform X1

    UniProtKB/Swiss-Prot
    A1L1J6
    UniProtKB/TrEMBL
    A6HIA9
    Conserved Domains (3) summary
    COG5048
    Location:438 → 487
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:380 → 463
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:386 → 406
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_039086630.2 → XP_038942558.1  zinc finger protein 652 isoform X2

    UniProtKB/TrEMBL
    A0A8I6G674
    Related
    ENSRNOP00000081616.1
    Conserved Domains (3) summary
    COG5048
    Location:258 → 307
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:200 → 283
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:206 → 226
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1L1J6.1 GenPept UniProtKB/Swiss-Prot:A1L1J6

Gene LinkOut

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